SynthesisJournal of autism and developmental disorders2015
Maternal Smoking and Autism Spectrum Disorder: A Meta-analysis.
Synthesis in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review.Translational psychiatry · 2021Pooled it
- Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators.Scientific reports · 2017Pooled it
- Association Between Maternal Obesity and Autism Spectrum Disorder in Offspring: A Meta-analysis.Journal of autism and developmental disorders · 2016Pooled it
- A Meta-Analysis of Maternal Smoking during Pregnancy and Autism Spectrum Disorder Risk in Offspring.International journal of environmental research and public health · 2015Pooled it
- Suicide attempt risk in autism: a national EHR study of 2.3 million individuals.Frontiers in psychiatry · 2026Article
- Article
- Maternal Smoking During Pregnancy and Risk of Autism Spectrum Disorder in Offspring: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- A Comprehensive Review on Plant-Based Medications and Chemical Approaches for Autism Spectrum Disorders (ASDs) Psychopharmacotherapy.Indian journal of microbiology · 2025Article
- Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders.Biochemical Society transactions · 2024Review
- Maternal Thyroid Dysfunction During Pregnancy as an Etiologic Factor in Autism Spectrum Disorder: Challenges and Opportunities for Research.Thyroid : official journal of the American Thyroid Association · 2024Review
- Environmental Risk Factors in Autism Spectrum Disorder: A Narrative Review.Current medicinal chemistry · 2024Review
- Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits.Advances in drug and alcohol research · 2023Review
- Beyond Genes: Germline Disruption in the Etiology of Autism Spectrum Disorders.Journal of autism and developmental disorders · 2022Article
- Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children.Journal of autism and developmental disorders · 2022Article
- Maternal tobacco smoking and offspring autism spectrum disorder or traits in ECHO cohorts.Autism research : official journal of the International Society for Autism Research · 2022Article
- Alcohol and Tobacco use While Breastfeeding and Risk of Autism Spectrum Disorder or Attention Deficit/Hyperactivity Disorder.Journal of autism and developmental disorders · 2022Article
- A biomarker-based study of prenatal smoking exposure and autism in a Finnish national birth cohort.Autism research : official journal of the International Society for Autism Research · 2021Article
- Prenatal exposure to paternal smoking and likelihood for autism spectrum disorder.Autism : the international journal of research and practice · 2021Article
- Smoking and Neuropsychiatric Disease-Associations and Underlying Mechanisms.International journal of molecular sciences · 2021Review
- Maternal Prenatal Smoking and Autism Spectrum Disorder in Offspring: A California Statewide Cohort and Sibling Study.American journal of epidemiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a meta-analysis of 15 studies on maternal prenatal smoking and ASD risk in offspring. Using a random-effects model, we found no evidence of an association (summary OR 1.02, 95% CI 0.93-1.12). Stratifying by study design, birth year, type of healthcare system, and adjustment for socioeconomic status or psychiatric history did not alter the findings. There was evidence that ascertaining exposure at the time of birth produced a lower summary OR than when this information was gathered after birth. There was no evidence of publication bias. Non-differential exposure misclassification was shown to have the potential for negligible influence on the results. We found no evidence to support a measurable association between maternal prenatal smoking and ASD in offspring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.