Evidence map›Paper›PMID 25431651›Full record

ArticleChemical science2014

Regioselective and Diastereoselective Aminoarylation of 1,3-Dienes.

Hongli Bao, Liela Bayeh, Uttam K Tambar

Abstract read
In one paragraph

Article in Chemical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Copper-Catalyzed Aminothiolation of 1,3-Dienes via a Dihydrothiazine Intermediate.Angewandte Chemie (International ed. in English) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongli BaoThe University of Texas Southwestern Medical Center at Dallas, Department of Biochemistry, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA. ; Tel: +1-214-648-0580.
Liela BayehThe University of Texas Southwestern Medical Center at Dallas, Department of Biochemistry, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA. ; Tel: +1-214-648-0580.
Uttam K TambarThe University of Texas Southwestern Medical Center at Dallas, Department of Biochemistry, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA. ; Tel: +1-214-648-0580.

Funding

Stereoselective Rearrangements for the Synthesis of Bioactive Small MoleculesR01GM102604 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI TAMBAR, UTTAM KRISHAN · 2012 to 2024
$5.0M
NIGMS NIH HHS R01 GM102604
6 · The paper itself

Abstract

The 1,4-functionalization of dienes is a synthetically useful strategy for incorporating molecular complexity into a class of simple substrates. We report the aminoarylation of acyclic and cyclic 1,3-dienes via the sequential [4+2] cycloaddition with a sulfurdiimide reagent and copper-catalyzed allylic substitution with Grignard reagents. The regioselective and diastereoselective aminoarylation of unsymmetrical dienes is also presented, which highlights the utility of this method for generating products with multiple functional groups and stereocenters.

Identifiers

PMID25431651
PMCPMC4242432

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.