Evidence map›Paper›PMID 25431647›Full record

ArticleMedChemComm2014

Anti-bacterial glycosyl triazoles - Identification of an N-acetylglucosamine derivative with bacteriostatic activity against Bacillus.

Helene Kuhn, Danielle Gutelius, Eimear Black, Christina Nadolny, Amit Basu, Christopher Reid

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. TargetingAntibiotics (Basel, Switzerland) · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helene KuhnDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.
Danielle GuteliusDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.
Eimear BlackDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.
Christina NadolnyDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.
Amit BasuDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.
Christopher ReidDepartment of Chemistry, Brown University, Providence RI 02912; Department of Science and Technology, Bryant University, Providence RI 02917.

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
NIGMS NIH HHS P20 GM103430
6 · The paper itself

Abstract

N-acetylglucosaminidases (GlcNAcases) play an important role in the remodeling and recycling of bacterial peptidoglycan. Inhibitors of bacterial GlcNAcases can serve as antibacterial agents and provide an opportunity for the development of new antibiotics. We report the synthesis of triazole derivatives of

Identifiers

PMID25431647
PMCPMC4241850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.