Evidence map›Paper›PMID 25431646›Full record

ArticleMedChemComm2014

Microfluidic continuous-flow radiosynthesis of [

Steven H Liang, Daniel L Yokell, Raul N Jackson, Peter A Rice, Ronald Callahan, Keith A Johnson, David Alagille, Gilles Tamagnan, Thomas Lee Collier, Neil Vasdev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Production of [Molecules (Basel, Switzerland) · 2022
    Article
  3. Article
  4. Review
  5. Revisiting the Radiosynthesis of [Molecules (Basel, Switzerland) · 2020
    Article
  6. Article
  7. FacileNature protocols · 2019
    Article
  8. Production of diverse PET probes with limited resources: 24Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  9. Microfluidic radiosynthesis of [Beilstein journal of organic chemistry · 2017
    Article
  10. Review
  11. Article
  12. Article
  13. Synthesis ofJournal of fluorine chemistry · 2015
    Article
  14. Australian journal of chemistry · 2015
    Article
  15. Iodonium ylide-mediated radiofluorination of 18F-FPEB and validation for human use.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Steven H LiangDepartment of Radiology, Harvard Medical School, 55 Fruit Street, Boston, MA, USA, 02114 ; Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
Daniel L YokellDivision of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
Raul N JacksonDivision of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
Peter A RiceDivision of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
Ronald CallahanDepartment of Radiology, Harvard Medical School, 55 Fruit Street, Boston, MA, USA, 02114 ; Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
Keith A JohnsonDepartment of Radiology, Harvard Medical School, 55 Fruit Street, Boston, MA, USA, 02114 ; Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.
David AlagilleMolecular NeuroImaging, LLC, New Haven, CT, 06510 ; Institute for Neurodegenerative Disorders, New Haven, CT, 06510.
Gilles TamagnanMolecular NeuroImaging, LLC, New Haven, CT, 06510 ; Institute for Neurodegenerative Disorders, New Haven, CT, 06510.
Thomas Lee CollierDepartment of Radiology, Harvard Medical School, 55 Fruit Street, Boston, MA, USA, 02114 ; Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114 ; Advion Inc., 10 Brown Road, Ithaca, NY, 14850.
Neil VasdevDepartment of Radiology, Harvard Medical School, 55 Fruit Street, Boston, MA, USA, 02114 ; Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114.

Funding

SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT)P01AG004953 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI KILLIANY, RONALD J · 1985 to 2006
$15.0M
New PET tracers for neuroimaging of FAAH in endocannabinoid signalingK01DA038000 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI LIANG, STEVEN H · 2014 to 2018
$927k
NIA NIH HHS P01 AG004953NIDA NIH HHS K01 DA038000
6 · The paper itself

Abstract

The synthesis of fluorine-18 labeled 3-fluoro-5-[(pyridin-3-yl)ethynyl] benzonitrile ([

Identifiers

PMID25431646
PMCPMC4243709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.