Evidence map›Paper›PMID 25431616›Full record

ArticleFuture virology2014

The RNA-dependent RNA polymerase of the influenza A virus.

Thomas M Stubbs, Aartjan Jw Te Velthuis

Open access · hybridAbstract read
In one paragraph

Article in Future virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Repurposing of the nucleoside analogs for influenza.Computational and structural biotechnology journal · 2025
    Article
  6. Naturally occurring PAVirologica Sinica · 2024
    Article
  7. Antiviral Approaches against Influenza Virus.Clinical microbiology reviews · 2023
    Review
  8. Article
  9. Article
  10. Frontiers in pharmacology · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Human endeavor for anti-SARS-CoV-2 pharmacotherapy: A major strategy to fight the pandemic.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. 1,2,4-Triazolo[1,5-a]pyrimidines in drug design.European journal of medicinal chemistry · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Thomas M StubbsSir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK ; Babraham Institute, Brabraham Research Campus, Cambridge, CB22 3AT, UK.
Aartjan Jw Te VelthuisSir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.
Babraham Institute · GBUniversity of Oxford · GB

Funding

Wellcome Trust 098721
6 · The paper itself

Abstract

The influenza A virus causes a highly contagious respiratory disease that significantly impacts our economy and health. Its replication and transcription is catalyzed by the viral RNA polymerase. This enzyme is also crucial for the virus, because it is involved in the adaptation of zoonotic strains. It is thus of major interest for the development of antiviral therapies and is being intensively studied. In this article, we will discuss recent advances that have improved our knowledge of the structure of the RNA polymerase and how mutations in the polymerase help the virus to spread effectively among new hosts.

Indexed as

adaptationhost restrictioninfluenza AreplicationRNA polymerasestructuretranscription

Identifiers

PMID25431616
PMCPMC4243023
OpenAlexW2103755768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.