Evidence map›Paper›PMID 25431230›Full record

ArticleNanoscale2015

Synthesis of nano-bowls with a Janus template.

Alexander H Mo, Preston B Landon, Chris D Emerson, Chen Zhang, Paula Anzenberg, Siddhartha Akkiraju, Ratnesh Lal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Preparation of Asymmetric AlMaterials (Basel, Switzerland) · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander H Mo *Materials Science and Engineering Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Preston B Landon *Dept. of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Chris D EmersonDept of Nanoengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Chen ZhangDept of Nanoengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Paula AnzenbergDept. of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Siddhartha AkkirajuDept of Nanoengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Ratnesh LalMaterials Science and Engineering Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.

Funding

Amyloid ion channels to design therapeutics for neurodegenerative diseasesR01AG028709 · NIA · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 2006 to 2018
$3.6M
Designing an Integrated Nanoscale System for Ion Channel Structure-Function StudyR01DA025296 · NIDA · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 2008 to 2013
$1.7M
Structure, Activity & Physiological Role of HemichannelsR01DA024871 · NIDA · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 2008 to 2012
$1.5M
Structure, Activity &Physiological Role of HemichannelsR01GM056290 · NIGMS · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 1997 to 2006
$1.5M
NIA NIH HHS R01 AG028709NIDA NIH HHS R01 DA024871NIDA NIH HHS R01DA024871NIDA NIH HHS R01 DA025296NIDA NIH HHS R01DA025296NIGMS NIH HHS R01 GM056290
6 · The paper itself

Abstract

Colloidal particles with two or more different surface properties (Janus particles) are of interest in catalysis, biological imaging, and drug delivery. Eccentric nanoparticles are a type of Janus particle consisting of a shell that envelops the majority of a core particle, leaving a portion of the core surface exposed. Previous work to synthesize eccentric nanoparticles from silica and polystyrene have only used microemulsion techniques. In contrast we report the sol-gel synthesis of eccentric Janus nanoparticles composed of a silica shell around a carboxylate-modified polystyrene core (Janus templates). In addition, we have synthesized nano-bowl-like structures after the removal of the polystyrene core by organic solvent. These Janus templates and nanobowls can be used as a versatile platform for site-specific functionalization or controlled theranostic delivery.

Indexed as

Carboxylic AcidsNanoparticlesNanostructuresParticle SizePolystyrenesSilicon DioxideSolventsSurface PropertiesCarboxylic AcidsPolystyrenesSilicon DioxideSolvents

Identifiers

PMID25431230
PMCPMC4353600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.