Evidence map›Paper›PMID 25431225›Full record

ArticleBMJ open2014

CUPID: a protocol of a randomised controlled trial to identify characteristics of similar Chinese patent medicines.

Hongbo Cao, Jingbo Zhai, Nan Li, Hongxia Cao, Xiang Lei, Wei Mu, Zhi Liu, Hui Wang, Hongcai Shang

Abstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongbo CaoTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China Center for Evidence-Based Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jingbo ZhaiTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Nan LiTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Hongxia CaoDepartment of Geriatrics, Gansu Hospital of Traditional Chinese Medicine, Lanzhou, China.
Xiang LeiCenter for Evidence-Based Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wei MuCenter for Evidence-Based Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID http://orcid.org/0000-0003-2369-7878
Zhi LiuTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Hui WangTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Hongcai ShangTianjin Institute of Clinical Evaluation, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTraditional Chinese medicine (TCM) has accumulated some experience in curing stable angina pectoris (SAP) and efficacy has been demonstrated. Chinese patent medicines, known as modern dosage forms of TCM, can attain the desired effect in clinical application only with the guidance of TCM syndrome theory. However, due to their use by a large number of persons with little knowledge of TCM theories and practices, their efficacy and reputation have been seriously affected. METHOD AND ANALYSIS: Two common syndrome types of SAP in TCM, 'qi deficiency and blood stasis' and 'qi stagnation and blood stasis', will be studied in 144 subjects from four TCM hospitals in Tianjin in China using a partial crossover design. The two syndromes will be broken down into six symptom combinations; patients will select a combination of the most distressing to them, and then will be randomised into two groups. Each group, on the basis of routine medication, will be administered one kind of Chinese patent drug: Qishenyiqi Dripping Pills or Compound Danshen Dripping Pills. The treatment characteristics of the two medicines will be evaluated with the COME-PIO method developed by our research team. ETHICS AND DISSEMINATION: This protocol has been approved by the medical ethics committee of Tianjin University of TCM (registration number TJUTCM-EC20130005). The study is safe and reliable. TRIAL REGISTRATION NUMBER: Chinese clinical trials register ChiCTR-TTRCC-14004406.

Indexed as

Angina, StableClinical ProtocolsMedicine, Chinese TraditionalNonprescription DrugsPhytotherapyRandomized Controlled Trials as TopicChinaCross-Over StudiesDrugs, Chinese HerbalHumansSalvia miltiorrhizadan-shen root extractDrugs, Chinese HerbalNonprescription DrugsCOMPLEMENTARY MEDICINESTATISTICS & RESEARCH METHODS

Identifiers

PMID25431225
PMCPMC4248088

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.