ReviewAIDS care2015
Inclusion of trans women in pre-exposure prophylaxis trials: a review.
Review in AIDS care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04050371 (I-BrEATHe - Interactions Between Antiretrovirals And Transgender Hormones), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
I-BrEATHe - Interactions Between Antiretrovirals And Transgender Hormones
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The worldwide burden of HIV in transgender individuals: An updated systematic review and meta-analysis.PloS one · 2021Pooled it
- Trial
- HIV pre-exposure prophylaxis in transgender women: a subgroup analysis of the iPrEx trial.The lancet. HIV · 2015Trial
- PrEP Disparities Among Transgender Feminine, Transgender Masculine, Nonbinary, and Gender Expansive Youth and Young Adults in the United States.AIDS and behavior · 2025Article
- Adaptation of a Theory-Based Mobile App to Improve Access to HIV Prevention Services for Transgender Women in Malaysia: Focus Group Study.JMIR formative research · 2024Article
- Barriers to Accessing and Engaging in HIV Preventive Care and Pre-Exposure Prophylaxis Experienced by Transgender Women in Florida.International journal of environmental research and public health · 2024Article
- PrEP Use and Adherence among Transgender Persons in Chicago, IL (SHIPP Study, 2014-2018, USA).AIDS and behavior · 2023Article
- The Continued Importance of Including Transgender Individuals in HIV-Related Research.AIDS research and human retroviruses · 2022Article
- Optimizing an mHealth Intervention to Improve Uptake and Adherence to HIV Pre-exposure Prophylaxis in Young Transgender Women: Protocol for a Multi-Phase Trial.JMIR research protocols · 2022Article
- Improved PrEP Awareness and Use among Trans Women in San Francisco, California.AIDS and behavior · 2022Article
- Exploring barriers and facilitators to PrEP use among transgender women in two urban areas: implications for messaging and communication.BMC public health · 2022Article
- Transgender Women's Barriers, Facilitators, and Preferences on Tailored Injection Delivery Strategies to Administer Long-Acting Injectable Cabotegravir (CAB-LA) for HIV Pre-exposure Prophylaxis (PrEP).AIDS and behavior · 2021Article
- FOREST protocol: a qualitative study exploring health and sexuality of transmasculine individuals in France.BMJ open · 2021Article
- Characterizing Biomedical HIV Prevention Awareness and Use Among Black Transgender Women in the United States.AIDS and behavior · 2021Article
- Global scoping review of HIV prevention research with transgender people: Transcending from trans-subsumed to trans-centred research.Journal of the International AIDS Society · 2021Article
- Pre-Exposure Prophylaxis (PrEP) for HIV Infection in Cisgender and Transgender Women in the U.S.: A Narrative Review of the Literature.Archives of sexual behavior · 2021Review
- Pre and Post-exposure Prophylaxis Awareness and Acceptability Among Sex Workers in Jamaica: A Cross-Sectional Study.AIDS and behavior · 2021Article
- Article
- Barriers and Facilitators to PrEP Initiation and Adherence Among Transgender and Gender Non-Binary Individuals in Southern California.AIDS education and prevention : official publication of the International Society for AIDS Education · 2020Article
- Characterizing PrEP Awareness and Interest Among Filipina Transgender Women.AIDS education and prevention : official publication of the International Society for AIDS Education · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Trans women are at high risk of HIV infection. We conducted a review to determine the extent to which trans women were eligible for inclusion in and enrolled into pre-exposure prophylaxis (PrEP) efficacy trials. Out of seven trials analyzing PrEP efficacy, we found that trans women comprised only 1.2% of one trial and 0.2% of total trial enrollments. Although an additional PrEP trial to determine efficacy among trans women may not be warranted, further research is needed to determine the effectiveness of PrEP in this marginalized population, through observational and feasibility studies. These studies should focus on unique barriers that trans women may experience while obtaining access to PrEP, such as gender discrimination, transphobia, and violence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.