Evidence map›Paper›PMID 25430600›Full record

ReviewSports medicine (Auckland, N.Z.)2015

Exercise with blood flow restriction: an updated evidence-based approach for enhanced muscular development.

Brendan R Scott, Jeremy P Loenneke, Katie M Slattery, Ben J Dascombe

8 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 177 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 17 pooled it
34.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04333784 completednot on this mapstarted 2020, after this paper: background citation

The Effect of Blood Flow Restriction Training on Muscle Thickness and Symptoms in Patients With Rotator Cuff Tendinopathy

TypeobservationalSponsorHacettepe UniversityRan2020 to 2022Enrolled32ConditionsRotator Cuff TendinosisArmsExercise training
NCT04484961 nacompletednot on this mapstarted 2016, after this paper: background citation

Effects of Blood Flow Restriction Rehabilitation After Bone Patellar Tendon Bone Anterior Cruciate Ligament Reconstruction

TypeinterventionalSponsorThe Methodist Hospital Research InstituteRan2016 to 2020Enrolled50ConditionsACL TearArmsBlood flow restriction (BFR)
NCT04521959 nacompletednot on this mapstarted 2020, after this paper: background citation

The Effect Of Blood Flow Restrıcted Resistive And Aerobic Exercises in Chronic Obstructive Pulmonary Patients

TypeinterventionalSponsorMedipol UniversityRan2020 to 2021Enrolled40ConditionsCopdArmsBlood flow restricted and normal aerobic exercise and resistance exercise
NCT04526184 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Systemic Effects of A Continuous Blood Flow Restricted Aerobic Exercise Session in COPD Patients: A Randomised Controlled Trial.

TypeinterventionalSponsorMedipol UniversityRan2020 to 2024Enrolled46ConditionsCOPDArmsaerobic exercise with blood flow restriction
NCT05538494 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Short-term Effects on the Patellar Tendon After Low-load Blood-flow Restriction Training Versus High-load Conventional Training. Randomized Clinical Trial.

TypeinterventionalSponsorUniversity of AlcalaRan2021 to 2022Enrolled84ConditionsPatellar TendinitisArmsBFR intervention, High load intervention
NCT05573321 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Blood Flow Restriction Exercise on Acute Systemic Irisin, Myostatin and Decorin Levels

TypeinterventionalSponsorEge UniversityRan2023 to 2023Enrolled22ConditionsMuscle HypotrophyArmsBFR-RE, HL-RE
NCT06480032 nacompletednot on this mapstarted 2023, after this paper: background citation

Low-Load Blood Flow Restriction Training vs Traditional Resistance Training Exercises Following Anterior Cruciate Ligament Reconstruction Surgery: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorAbasyn University PeshawarRan2023 to 2024Enrolled32ConditionsStrength, Range of Motion, Pain-Knee, Skeletal Muscle HypertrophyArmsBlood Flow Restriction band
NCT07141316 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty: Randomized Controlled Trial

TypeinterventionalSponsorUniversity of PaviaRan2025 to 2026Enrolled60ConditionsOsteo Arthritis KneeArmsBlood flow restriction combined with electrostimulation.
3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 17 syntheses or guidelines pooled it, 444 citations in OpenAlex.

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  14. Maximizing Muscle Hypertrophy: A Systematic Review of Advanced Resistance Training Techniques and Methods.International journal of environmental research and public health · 2019
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117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Brendan R ScottApplied Sports Science and Exercise Testing Laboratory, Faculty of Science and Information Technology, University of Newcastle, PO Box 127, Ourimbah, NSW, 2258, Australia, brendan.scott@uon.edu.au.
Jeremy P Loenneke
Katie M Slattery
Ben J Dascombe
Olympic Park Sports Medicine Centre · AUUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing body of evidence supports the use of moderate blood flow restriction (BFR) combined with low-load resistance exercise to enhance hypertrophic and strength responses in skeletal muscle. Research also suggests that BFR during low-workload aerobic exercise can result in small but significant morphological and strength gains, and BFR alone may attenuate atrophy during periods of unloading. While BFR appears to be beneficial for both clinical and athletic cohorts, there is currently no common consensus amongst scientists and practitioners regarding the best practice for implementing BFR methods. If BFR is not employed appropriately, there is a risk of injury to the participant. It is also important to understand how variations in the cuff application can affect the physiological responses and subsequent adaptation to BFR training. The optimal way to manipulate acute exercise variables, such as exercise type, load, volume, inter-set rest periods and training frequency, must also be considered prior to designing a BFR training programme. The purpose of this review is to provide an evidence-based approach to implementing BFR exercise. These guidelines could be useful for practitioners using BFR training in either clinical or athletic settings, or for researchers in the design of future studies investigating BFR exercise.

Indexed as

Evidence-Based MedicineExerciseHumansMuscle, SkeletalMuscle StrengthMuscular AtrophyRegional Blood FlowResistance Training

Identifiers

PMID25430600
OpenAlexW1988967372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.