Evidence map›Paper›PMID 25430084›Full record

ArticleInternational journal of hematology2015

Successful pregnancy and delivery via in vitro fertilization with cryopreserved and thawed embryo transfer in an acute myeloid leukemia patient after allogeneic bone marrow transplantation.

Yuki Nakajima, Hideyuki Kuwabara, Kumiko Kishimoto, Ayumi Numata, Kenji Motohashi, Takayoshi Tachibana, Masatsugu Tanaka, Naoki Yamashita, Yoshiaki Ishigatsubo, Shin Fujisawa

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In one paragraph

Article in International journal of hematology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Oocyte collection and outcome following oncologic treatment: a retrospective multicentre study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  3. Engaging Patients in Setting a Patient-Centered Outcomes Research Agenda in Hematopoietic Cell Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yuki NakajimaDepartment of Hematology, Yokohama City University Medical Center, Minami-ku Urafune-cho 4-57, Yokohama, Kanagawa, 232-0024, Japan, yuki1234@yokohama-cu.ac.jp.
Hideyuki Kuwabara
Kumiko Kishimoto
Ayumi Numata
Kenji Motohashi
Takayoshi Tachibana
Masatsugu Tanaka
Naoki Yamashita
Yoshiaki Ishigatsubo
Shin Fujisawa
Yokohama City University · JPYokohama City University Medical Center · JPClinica Santa Maria · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the number of young long-term survivors of hematopoietic stem cell transplantation (HSCT) for acute leukemia continues to increase, post-transplant infertility is becoming a significant concern. HSCT, particularly with cyclophosphamide and total body irradiation conditioning, is known to cause secondary premature ovarian failure, resulting in infertility. To preserve post-transplant fertility, several methods have been proposed, including in vitro fertilization (IVF) with embryo cryopreservation. Due to the aggressiveness of acute leukemia, however, patients have little chance to undergo egg harvesting and IVF before they must begin receiving chemotherapy. To the best of our knowledge, there have been no detailed reports of successful pregnancy after HSCT using IVF with embryo cryopreservation and transfer in a patient with acute myeloid leukemia. Here, we report the case of a 42-year-old woman with acute myeloid leukemia who became pregnant 2 years and 2 months after allogeneic bone marrow transplantation via IVF-embryo transfer with an egg collected after induction therapy and delivered a full-term healthy infant.

Indexed as

Bone Marrow TransplantationEmbryo TransferAdultCryopreservationDelivery, ObstetricFemaleFertilization in VitroHumansInfant, NewbornLeukemia, Myeloid, AcuteLive BirthPregnancyPregnancy Complications, NeoplasticTransplantation, Homologous

Identifiers

PMID25430084
OpenAlexW2025389789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.