Evidence map›Paper›PMID 25429922›Full record

ReviewProteomics2015

Current peptidomics: applications, purification, identification, quantification, and functional analysis.

David C Dallas, Andres Guerrero, Evan A Parker, Randall C Robinson, Junai Gan, J Bruce German, Daniela Barile, Carlito B Lebrilla

Abstract readReview
In one paragraph

Review in Proteomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 230 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Frontiers in pharmacology · 2026
    Article
  8. Mass Spectrometry for Proteomics-Based Investigation.Advances in experimental medicine and biology · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Quantification of Peptides in Food Hydrolysate fromFoods (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David C DallasDepartment of Food Science and Technology, University of California, Davis, One Shields Avenue, Davis, CA, USA; Foods for Health Institute, University of California, Davis, One Shields Avenue, Davis, CA, USA.
Andres Guerrero
Evan A Parker
Randall C Robinson
Junai Gan
J Bruce German
Daniela Barile
Carlito B Lebrilla
University of California, Davis · US

Funding

The incorporation of human milk oligosaccharides in brain glycoconjugatesR01GM049077 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI LEBRILLA, CARLITO B · 1999 to 2024
$6.3M
Structures, Functions, & Genetic Diversity of Oligosaccharides in MilkR01HD061923 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEBRILLA, CARLITO B · 2009 to 2013
$1.6M
Deciphering the function of naturally occurring peptides in human milkR00HD079561 · NICHD · OREGON STATE UNIVERSITY · PI DALLAS, DAVID CHARLES · 2016 to 2018
$741k
Deciphering the function of naturally occurring peptides in human milkK99HD079561 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DALLAS, DAVID CHARLES · 2014 to 2015
$157k
NICHD NIH HHS K99 HD079561NICHD NIH HHS K99HD079561NICHD NIH HHS R00 HD079561NICHD NIH HHS R01 HD061923NICHD NIH HHS R01HD061923NIGMS NIH HHS HD R01GM049077NIGMS NIH HHS R01 GM049077
6 · The paper itself

Abstract

Peptidomics is an emerging field branching from proteomics that targets endogenously produced protein fragments. Endogenous peptides are often functional within the body-and can be both beneficial and detrimental. This review covers the use of peptidomics in understanding digestion, and identifying functional peptides and biomarkers. Various techniques for peptide and glycopeptide extraction, both at analytical and preparative scales, and available options for peptide detection with MS are discussed. Current algorithms for peptide sequence determination, and both analytical and computational techniques for quantification are compared. Techniques for statistical analysis, sequence mapping, enzyme prediction, and peptide function, and structure prediction are explored.

Indexed as

Peptide FragmentsAnimalsBiomarkersCattleDietary ProteinsDigestionFood AnalysisHumansInfantMass SpectrometryProtein ConformationProteomicsSequence Analysis, ProteinSystems BiologyBiomarkersDietary ProteinsPeptide FragmentsFunctional predictionMSPeptidomicsQuantitationStructure predictionSystems biology

Identifiers

PMID25429922
PMCPMC4371869
OpenAlexW2097313508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.