Evidence map›Paper›PMID 25429916›Full record

ArticleTropical medicine & international health : TM & IH2015

Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru.

L Otero, A De Orbegoso, A F Navarro, J Ríos, T Párraga, E Gotuzzo, C Seas, P Van der Stuyft

Open access · bronzeAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Time to treatment for rifampicin-resistant tuberculosis: systematic review and meta-analysis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2017
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

L OteroInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru; Unit of General Epidemiology and Disease Control, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
A De Orbegoso
A F Navarro
J Ríos
T Párraga
E Gotuzzo
C Seas
P Van der Stuyft
Universidad Peruana Cayetano Heredia · PEInstituut voor Tropische Geneeskunde · BE

Funding

Program for Advanced ReseArch Capacities for AIDS in Peru (PARACAS): harnessing implementation science to enhance care and reduce transmission of HIVD43TW009763 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GOTUZZO, EDUARDO, ZUNT, JOSEPH RAYMOND · 2014 to 2024
$3.2M
Peru ICOHRTA Network for AIDS/TB Research TrainingU2RTW007368 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GOTUZZO, EDUARDO · 2007 to 2011
$1.8M
Peru ICOHRTA Network for AIDS/TB Research TrainingU2RTW007374 · FIC · UNIVERSITY OF WASHINGTON · PI HOLMES, KING K. · 2007 to 2012
$1.2M
FIC NIH HHS D43 TW009763FIC NIH HHS U2R TW007368FIC NIH HHS U2R TW007374
6 · The paper itself

Abstract

objectiveTo determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru.

methodsWe studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011.

resultsTime from the first positive smear to MDR-TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days.

conclusionStart of and switching to MDR TB treatment is still delayed.

Indexed as

AdultAntitubercular AgentsDrug SubstitutionFemaleHumansIncidenceMaleOutcome Assessment, Health CarePeruRetrospective StudiesTime FactorsTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryAntitubercular Agentsmultidrug resistantmultirésistantemultirresistentePérouPeruPerútemps jusqu'au traitementTiempo hasta el inicio del tratamientotime to treatmenttuberculosetuberculosisTuberculosis

Identifiers

PMID25429916
PMCPMC4863977
OpenAlexW2111525165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.