Evidence map›Paper›PMID 25429838›Full record

SynthesisMedical oncology (Northwood, London, England)2015

Sentinel-lymph-node procedures in early stage cervical cancer: a systematic review and meta-analysis.

Xiao-Juan Wang, Fang Fang, Ye-Fei Li

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Medical oncology (Northwood, London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Diagnosis, Treatment, and Aftercare of Cervical Carcinoma.Deutsches Arzteblatt international · 2021
    Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Present status of sentinel lymph node biopsy in cervical cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiao-Juan WangObstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Shanghai, 200011, People's Republic of China.
Fang Fang
Ye-Fei Li
Obstetrics and Gynecology Hospital of Fudan University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a meta-analysis to assess the accuracy of sentinel-lymph-node (SLN) procedures for the assessment of nodal metastases in patients with early stage cervical cancer. Studies of SLN procedures for detecting nodal metastases in patients with early stage cervical cancer were systematically searched in MEDLINE and EMBASE between January 1, 2000 and August 30, 2013. We identified 49 eligible studies, which included 2,476 SLN procedures. The mean overall weighted-detection rate was 0.93 (95 % CI 0.92-0.94), at a pooled sensitivity of 0.88 (95 % CI 0.84-0.90) with limited heterogeneity (χ (2) = 80.57, degrees of freedom = 47, p = 0.002). Subgroup analysis of sensitivity and the rate of detection of different tracer techniques and surgery methods used in conjunction with an SLN procedures were as follows: studies using combined techniques, 0.88 (95 % CI 0.84-0.91) and 0.97 (95 % CI 0.96-0.98); studies using metastable technetium-99, 0.87 (95 % CI 0.78-0.93) and 0.90 (95 % CI 0.87-0.93); studies using blue dye, 0.87 (95 % CI 0.79-0.93) and 0.87 (95 % CI 0.84-0.90); studies using laparotomy, 0.86 (95 % CI 0.80-0.90) and 0.87 (95 % CI 0.83-0.91); studies using laparoscopy, 0.90 (95 % CI 0.86-0.94) and 0.93 (95 % CI 0.90-0.96); and studies using robot-assisted surgery, 0.84 (95 % CI 0.72-0.92) and 0.92 (95 % CI 0.88-0.95). We concluded that the SLN procedure performs well diagnostically for the assessment of nodal metastases in patients with early stage cervical cancer.

Indexed as

FemaleHumansLymphatic MetastasisNeoplasm StagingSentinel Lymph Node BiopsyUterine Cervical Neoplasms

Identifiers

PMID25429838
PMCPMC4246132
OpenAlexW2003322911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.