SynthesisScientific reports2014
The effect of chronic bacterial prostatitis on semen quality in adult men: a meta-analysis of case-control studies.
Synthesis in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Microbiota and seminal quality: A systematic review.JBRA assisted reproduction · 2023Pooled it
- Chronic prostatitis and its detrimental impact on sperm parameters: a systematic review and meta-analysis.Journal of endocrinological investigation · 2017Pooled it
- Urogenital Infection as a Risk Factor for Male Infertility.Deutsches Arzteblatt international · 2017Pooled it
- Article
- Probiotics as Microbiome Modulators in Male Infertility: Rethinking Dysbiosis Across the Gut-Testis Axis.Journal of personalized medicine · 2026Review
- Research progress on the multidimensional mechanisms underlying impaired spermatogenesis induced by pathological microenvironment remodeling in chronic prostatitis.Frontiers in immunology · 2026Review
- Testicular immunity.Molecular aspects of medicine · 2024Review
- Chronic Prostatitis/Chronic Pain Pelvic Syndrome and Male Infertility.Life (Basel, Switzerland) · 2023Review
- Ejaculatory Abstinence Affects the Sperm Quality in Normozoospermic Men-How Does the Seminal Bacteriome Respond?International journal of molecular sciences · 2023Article
- Article
- Reactive Oxygen Species in the Reproductive System: Sources and Physiological Roles.Advances in experimental medicine and biology · 2022Article
- Current Insights and Latest Updates in Sperm Motility and Associated Applications in Assisted Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- Bacteriospermia - A formidable player in male subfertility.Open life sciences · 2022Review
- Microbiota, Prostatitis, and Fertility: Bacterial Diversity as a Possible Health Ally.Advances in urology · 2021Article
- Article
- Pharmacological Interventions for Bacterial Prostatitis.Frontiers in pharmacology · 2020Review
- [Effect of semen bacterial infection on semen parameters and analysis of drug resistance in 74376 male infertility patients].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Letter to the Editor regarding the Article: "Anti-Inflammatory and Antimicrobial Effects of a Novel Herbal Formulation (WSY-1075) in a Chronic Bacterial Prostatitis Rat Model" by Park et al. World J Mens Health 2016;34(3):179-185.The world journal of men's health · 2018Article
- [Infection and infertility].Der Urologe. Ausg. A · 2016Review
- The Roles of Tight Junctions and Claudin-1 in the Microbubble-Mediated Ultrasound-Induced Enhancement of Drug Concentrations in Rat Prostate.The Journal of membrane biology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic bacterial prostatitis (CBP) is caused by bacterial infection and maintains a condition of lower urinary tract infection. It may be a cause of male infertility. However, studies showed inconsistent results regarding the effect of CBP on several parameters of semen. Hence, we conducted a meta-analysis to examine the effect of CBP on basic semen parameters. A systematic review was conducted with Medline, PubMed, EMBASE, and two Chinese databases (CNKI and WANG FANG) to identify relevant studies that involved the effect of CBP on semen parameters up to July 2014. Both RevMan5.2 and STATA 12.0 software were used for the statistical analysis. Based on the inclusion and exclusion criteria, seven studies were included. The study illustrated that sperm vitality, sperm total motility, and the percentage of progressively motile sperm from CBP patients were significantly lower than controls (SMD(95%CI) -0.81[-1.14, -0.47], -1.00[-1.28, -0.73], -0.41 [-0.70, -0.12], P<0.05, respectively). However, CBP had no significant effect on semen volume, sperm concentration and the duration of semen liquefaction. In summary, our study revealed that there was a significant negative effect of CBP on sperm vitality, sperm total motility, and the percentage of progressively motile sperm. Additional, studies with larger number of subjects are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.