ArticleNature communications2014
Evolution of dominance mechanisms at a butterfly mimicry supergene.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 125 citations in OpenAlex.
- Phenotypic dominance emerges from activity fitness functions and molecular interactions.Genetics · 2026Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.Evolution; international journal of organic evolution · 2026Article
- Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts.Current biology : CB · 2025Article
- Evolution of Large Polymorphic Inversions in a Panmictic Songbird.Molecular biology and evolution · 2025Article
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.bioRxiv : the preprint server for biology · 2025Article
- The potential of inversions to accumulate balanced sexual antagonism is supported by simulations andeLife · 2025Article
- Dominance reversals: the resolution of genetic conflict and maintenance of genetic variation.Proceedings. Biological sciences · 2024Review
- Penetrance interactions of colour pattern loci in the African Monarch and their implications for the evolution of dominance.Ecology and evolution · 2024Article
- Major patterns in the introgression history ofeLife · 2023Article
- Convergence in sympatric swallowtail butterflies reveals ecological interactions as a key driver of worldwide trait diversification.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A major 6 Mb superlocus is involved in pyrethroid resistance in the common bed bugEvolutionary applications · 2023Article
- Disruptive selection and the evolution of discrete color morphs inScience advances · 2023Article
- Article
- Radiation and hybridization underpin the spread of the fire ant social supergene.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Association mapping of colour variation in a butterfly provides evidence that a supergene locks together a cluster of adaptive loci.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- The integrative biology of genetic dominance.Biological reviews of the Cambridge Philosophical Society · 2021Review
- Ecological basis and genetic architecture of crypsis polymorphism in the desert clicker grasshopper (Ligurotettix coquilletti).Evolution; international journal of organic evolution · 2021Article
- Using comprehensive machine-learning models to classify complex morphological characters.Ecology and evolution · 2021Article
- Do floral and ecogeographic isolation allow the co-occurrence of two ecotypes ofEcology and evolution · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic dominance in polymorphic loci may respond to selection; however, the evolution of dominance in complex traits remains a puzzle. We analyse dominance at a wing-patterning supergene controlling local mimicry polymorphism in the butterfly Heliconius numata. Supergene alleles are associated with chromosomal inversion polymorphism, defining ancestral versus derived alleles. Using controlled crosses and the new procedure, Colour Pattern Modelling, allowing whole-wing pattern comparisons, we estimate dominance coefficients between alleles. Here we show strict dominance in sympatry favouring mimicry and inconsistent dominance throughout the wing between alleles from distant populations. Furthermore, dominance among derived alleles is uncoordinated across wing-pattern elements, producing mosaic heterozygous patterns determined by a hierarchy in colour expression. By contrast, heterozygotes with an ancestral allele show complete, coordinated dominance of the derived allele, independently of colours. Therefore, distinct dominance mechanisms have evolved in association with supergene inversions, in response to strong selection on mimicry polymorphism.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.