Evidence map›Paper›PMID 25429530›Full record

ArticleScientific reports2014

Direct evidence of milk consumption from ancient human dental calculus.

C Warinner, J Hendy, C Speller, E Cappellini, R Fischer, C Trachsel, J Arneborg, N Lynnerup, O E Craig, D M Swallow and 13 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 243 citations in OpenAlex.

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  19. Dairying and the evolution and consequences of lactase persistence in humans.Animal frontiers : the review magazine of animal agriculture · 2023
    Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 6 countries.

C Warinner1] Department of Anthropology, University of Oklahoma, Norman, OK, USA [2] Institute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.
J HendyBioArCh, Department of Archaeology, University of York, York, UK.
C SpellerBioArCh, Department of Archaeology, University of York, York, UK.
E CappelliniCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark.
R FischerHenry Wellcome Building for Cellular and Molecular Physiology, Oxford, UK.
C TrachselFunctional Genomics Center Zürich, University of Zürich/Swiss Federal Institute of Technology (ETH) Zürich, Zürich, Switzerland.
J Arneborg1] National Museum of Denmark, Copenhagen, Denmark [2] School of GeoSciences, University of Edinburgh, Edinburgh, United Kingdom.
N LynnerupLaboratory of Biological Anthropology, Institute of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, Denmark.
O E CraigBioArCh, Department of Archaeology, University of York, York, UK.
D M SwallowResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
A Fotakis1] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark [2] Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
R J ChristensenNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
J V OlsenNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
A LiebertResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
N Montalva1] Research Department of Genetics, Evolution and Environment, University College London, London, UK [2] Department of Anthropology, University College London, London UK.
S FiddymentBioArCh, Department of Archaeology, University of York, York, UK.
S CharltonBioArCh, Department of Archaeology, University of York, York, UK.
M MackieBioArCh, Department of Archaeology, University of York, York, UK.
A CanciDipartimento di Archeologia, Università degli Studi di Padova, Padova, Italy.
A BouwmanInstitute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.
F RühliInstitute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.
M T P Gilbert1] Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark [2] Trace and Environmental DNA Laboratory, Department of Environment and Agriculture, Curtin University, Perth, Australia.
M J CollinsBioArCh, Department of Archaeology, University of York, York, UK.
University of York · GBUniversity of Copenhagen · DKUniversity College London · GBUniversity of Zurich · CHCurtin University · AUNovo Nordisk Foundation · DKUniversity of Edinburgh · GBUniversity of Oklahoma · USUniversity of Padua · IT

Funding

Wellcome TrustWellcome Trust 097829/Z/11/A
6 · The paper itself

Abstract

Milk is a major food of global economic importance, and its consumption is regarded as a classic example of gene-culture evolution. Humans have exploited animal milk as a food resource for at least 8500 years, but the origins, spread, and scale of dairying remain poorly understood. Indirect lines of evidence, such as lipid isotopic ratios of pottery residues, faunal mortality profiles, and lactase persistence allele frequencies, provide a partial picture of this process; however, in order to understand how, where, and when humans consumed milk products, it is necessary to link evidence of consumption directly to individuals and their dairy livestock. Here we report the first direct evidence of milk consumption, the whey protein β-lactoglobulin (BLG), preserved in human dental calculus from the Bronze Age (ca. 3000 BCE) to the present day. Using protein tandem mass spectrometry, we demonstrate that BLG is a species-specific biomarker of dairy consumption, and we identify individuals consuming cattle, sheep, and goat milk products in the archaeological record. We then apply this method to human dental calculus from Greenland's medieval Norse colonies, and report a decline of this biomarker leading up to the abandonment of the Norse Greenland colonies in the 15(th) century CE.

Indexed as

AnimalsArchaeologyBiological EvolutionCattleDairy ProductsDental CalculusHumansLactoglobulinsMilkSheepTandem Mass SpectrometryLactoglobulins

Identifiers

PMID25429530
PMCPMC4245811
OpenAlexW2094697682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.