ArticleTranslational cancer research2013
Improving chemoradiotherapy with nanoparticle therapeutics.
Article in Translational cancer research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Nanomaterials reshaping cancer radiotherapy: Radiosensitization mechanisms, delivery and theranostic platforms, multimodal synergy, and clinical translation strategies.Materials today. Bio · 2026Review
- T Cell and Natural Killer Cell Membrane-Camouflaged Nanoparticles for Cancer and Viral Therapies.ACS applied bio materials · 2024Review
- Review
- Matrices and Affinity Ligands for Antibody Purification and Corresponding Applications in Radiotherapy.Biomolecules · 2022Review
- Evolving role of biomaterials in diagnostic and therapeutic radiation oncology.Bioactive materials · 2020Review
- Gold Nanoparticles as Radiosensitizers in Cancer Radiotherapy.International journal of nanomedicine · 2020Review
- Delivery of Nanoparticle-Based Radiosensitizers for Radiotherapy Applications.International journal of molecular sciences · 2019Review
- Radiosensitization Effects by Bismuth Oxide Nanoparticles in Combination with Cisplatin for High Dose Rate Brachytherapy.International journal of nanomedicine · 2019Article
- Nanotechnology for Cancer Therapy Based on Chemotherapy.Molecules (Basel, Switzerland) · 2018Review
- Capacity of gold nanoparticles in cancer radiotherapy.Japanese journal of radiology · 2017Review
- Long-term tolerance and cardiac function in breast cancer patients receiving trastuzumab therapy.Oncotarget · 2017Article
- Rethinking cancer nanotheranostics.Nature reviews. Materials · 2017Article
- EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.International journal of radiation biology · 2016Article
- Application of nanotechnology to cancer radiotherapy.Cancer nanotechnology · 2016Review
- Polymer nanostructures synthesized by controlled living polymerization for tumor-targeted drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2015Review
- Mediastinoscopic esophagectomy for patients with early esophageal cancer.Journal of thoracic disease · 2015Article
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Authors and funding
2 authors.
Funding
Abstract
Chemoradiotherapy has been a key treatment paradigm in cancer management. One of the main research objectives in cancer research has been to identify agents and strategies to improve the therapeutic index of chemoradiation. Recent development of nanoparticle (NP)-based chemotherapeutics offers a unique opportunity to improve the delivery of chemotherapy, which can in turn improve chemoradiotherapy's efficacy while lowering toxicity. NP-based chemotherapeutics also possess several characteristics that are well suited for chemoradiotherapy. Therefore, NP chemotherapeutics hold high potential in improving the therapeutic index of chemoradiotherapy. This manuscript reviews the NP properties that are favorable for chemoradiation and the rationale to utilize nanotherapeutics in chemoradiation. This review also discusses the preclinical and clinical data on using NP therapeutics in chemoradiotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.