Evidence map›Paper›PMID 25429347›Full record

ArticleIranian journal of basic medical sciences2014

The effects of Eucheuma cottonii on alveolar macrophages and malondialdehyde levels in bronchoalveolar lavage fluid in chronically particulate matter 10 coal dust-exposed rats.

Romadhiyana Kisno Saputri, Bambang Setiawan, Dian Nugrahenny, Nia Kania, Endang Sri Wahyuni, M Aris Widodo

Abstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Anti-Inflammatory and Anti-Remodelling Potential of Ethanol ExtractReports of biochemistry & molecular biology · 2022
    Article
  3. Review
  4. Review
  5. Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Romadhiyana Kisno SaputriFaculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
Bambang SetiawanDepartment of Medical Chemistry and Biochemistry, Research Center for Toxicology, Cancer and Degenerative Disease, Medical Faculty, Lambung Mangkurat University, Banjarmasin, South Kalimantan, Indonesia.
Dian NugrahennyLaboratory of Pharmacology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
Nia KaniaDepartment of Pathology, Research Center for Toxicology, Cancer and Degenerative Disease, Ulin General Hospital, Medical Faculty, Lambung Mangkurat University, Banjarmasin, South Kalimantan, Indonesia.
Endang Sri WahyuniLaboratory of Physiology; Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
M Aris WidodoLaboratory of Pharmacology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of Eucheuma cottonii on alveolar macrophages (AM) and malondialdehyde (MDA) levels in bronchoalveolar lavage fluids (BALF) in particulate matter 10 (PM10) coal dust-exposed rats. MATERIALS AND

methodsTen groups, including a non exposed group and groups exposed to coal dust at doses of 6.25 (CD6.25), 12.5 (CD12.5), or 25 mg/m(3) (CD25) an hour daily for 6 months with or without supplementation of ethanolic extract of E. cottonii at doses of 150 (EC150) or 300 mg/kg BW (EC300). The number of macrophages was determined using a light microscope. MDA levels were measured by TBARS assay.

resultsEC150 insignificantly (P > 0.05) reduces the AM in CD groups compared to non treatment groups. EC150 and EC300 significantly (P < 0.05) decreased MDA levels in CD12.5 and CD25 groups relative to non treatment groups.

conclusionE. cottonii attenuated oxidative stress in chronic exposure of PM10 coal dust.

Indexed as

Alveolar macrophageCoal dustEucheuma cottoniiMalondialdehyde

Identifiers

PMID25429347
PMCPMC4242926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.