Evidence map›Paper›PMID 25429195›Full record

ArticlePsoriasis forum2012

Biomarkers to Diagnose Early Arthritis in Patients With Psoriasis.

Ya-Hui Grace Chiu, Christopher T Ritchlin

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Psoriasis forum, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. DC-STAMP: A Key Regulator in Osteoclast Differentiation.Journal of cellular physiology · 2016
    Review
  3. Review
  4. Characterization of DC-STAMP+ Cells in Human Bone Marrow.Journal of bone marrow research · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ya-Hui Grace ChiuAllergy/Immunology & Rheumatology, University of Rochester Medical School, Rochester, New York.
Christopher T RitchlinAllergy/Immunology & Rheumatology, University of Rochester Medical School, Rochester, New York.
University of Rochester · US

Funding

Osteoclastic Bone Resorption in Psoriatic ArthritisK23AR047816 · NIAMS · UNIVERSITY OF ROCHESTER · PI RITCHLIN, CHRISTOPHER T · 2001 to 2003
$379k
NIAMS NIH HHS K23 AR047816
6 · The paper itself

Abstract

backgroundPsoriatic arthritis is a potentially destructive, inflammatory joint disease that affects 20% to 30% of patients with psoriasis. Psoriasis precedes the onset of joint inflammation by approximately 10 years, providing a unique opportunity to intervene and prevent or delay onset of musculoskeletal manifestations. The emergence of sensitive imaging modalities and cellular biomarkers may facilitate early identification of patients with psoriasis who have subclinical joint disease and might help stratify patients with an early onset of arthritis.

methodsThe translational studies described herein are focused on the development of cellular biomarkers identified with flow cytometry and cell culture techniques in patients with psoriasis and psoriatic arthritis. RESULTS AND

conclusionThe combination of power Doppler ultrasound imaging and cellular biomarkers (ie, CD16 and dendritic cell specific transmembrane protein) to diagnose early psoriatic arthritis and to stratify patients with established psoriatic arthritis provides a new opportunity to optimize treatment outcomes in this potentially disabling disease.

Indexed as

biomarkerCD16cell fusionDC-STAMPosteoclastPsoriasispsoriatic arthritissignaling

Identifiers

PMID25429195
PMCPMC4241968
OpenAlexW2263518146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.