ArticleProceedings. Biological sciences2015
Interspecific competition in honeybee intracellular gut parasites is asymmetric and favours the spread of an emerging infectious disease.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of honey bee (Apis mellifera, Linnaeus, 1758) infections and available treatment options.Veterinary medicine and science · 2023Pooled it
- Development of a potential vaccine against dengue and chikungunya virus co-infection using immunoinformatics and structural evaluation.Journal, genetic engineering & biotechnology · 2026Article
- Counterproductive: coinfection of a water flea by a fungus and a microsporidium reduces the reproductive outputs of all parties.Scientific reports · 2026Article
- An Overview of the Most Commonly Used Methods for the Detection ofMicroorganisms · 2025Review
- Pathogen growth and virulence dynamics drive the host evolution against coinfections.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Fall Treatment with Fumagillin Contributes to an Overwinter Shift inLife (Basel, Switzerland) · 2024Article
- The first arriving virus shapes within-host viral diversity during natural epidemics.Proceedings. Biological sciences · 2023Article
- Poor Air Quality Is Linked to Stress in Honeybees and Can Be Compounded by the Presence of Disease.Insects · 2023Article
- Geographic population structure of the honeybee microsporidian parasite Vairimorpha (Nosema) ceranae in the South West Indian Ocean.Scientific reports · 2023Article
- Preliminary Survey of Pathogens in the Asian Honey Bee (Life (Basel, Switzerland) · 2023Article
- Epidemiology of the MicrosporidiumInsects · 2022Article
- Epidemiology of a major honey bee pathogen, deformed wing virus: potential worldwide replacement of genotype A by genotype B.International journal for parasitology. Parasites and wildlife · 2022Article
- Increased alarm pheromone component is associated withRoyal Society open science · 2021Article
- Infected juvenile salmon can experience increased predation during freshwater migration.Royal Society open science · 2021Article
- Urbanization is associated with shifts in bumblebee body size, with cascading effects on pollination.Evolutionary applications · 2021Article
- Sequential co-infections drive parasite competition and the outcome of infection.The Journal of animal ecology · 2020Article
- Honey as a Source of Environmental DNA for the Detection and Monitoring of Honey Bee Pathogens and Parasites.Veterinary sciences · 2020Article
- Article
- Impact of Mixed Infections of Gut ParasitesInsects · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
There is increasing appreciation that hosts in natural populations are subject to infection by multiple parasite species. Yet the epidemiological and ecological processes determining the outcome of mixed infections are poorly understood. Here, we use two intracellular gut parasites (Microsporidia), one exotic and one co-evolved in the western honeybee (Apis mellifera), in an experiment in which either one or both parasites were administered either simultaneously or sequentially. We provide clear evidence of within-host competition; order of infection was an important determinant of the competitive outcome between parasites, with the first parasite significantly inhibiting the growth of the second, regardless of species. However, the strength of this 'priority effect' was highly asymmetric, with the exotic Nosema ceranae exhibiting stronger inhibition of Nosema apis than vice versa. Our results reveal an unusual asymmetry in parasite competition that is dependent on order of infection. When incorporated into a mathematical model of disease prevalence, we find asymmetric competition to be an important predictor of the patterns of parasite prevalence found in nature. Our findings demonstrate the wider significance of complex multi-host-multi-parasite interactions as drivers of host-pathogen community structure.
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