ArticleJournal of experimental botany2015
TaHsfA6f is a transcriptional activator that regulates a suite of heat stress protection genes in wheat (Triticum aestivum L.) including previously unknown Hsf targets.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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85 citing papers in PubMed, 187 citations in OpenAlex.
- Heat stress responses of plants during adaptation to high temperature environments: A review of recent advances and insights.Plant signaling & behavior · 2026Review
- Advancing climate adaptation in saffron through CRISPR-based modulation of stress tolerance and photoperiodic flowering control.GM crops & food · 2026Review
- Design Principles of Plant Thermotolerance: Integrating Photosynthesis, Reproduction, and Field Resilience in a Warming Climate.Plant, cell & environment · 2026Review
- Genome-wide analysis of the HSF gene family in lily and functional characterization of LdHSFC1 under heat stress.Plant cell reports · 2026Article
- Harnessing genomics approaches for heat stress resilience in wheat: from discovery to deployment.Journal of experimental botany · 2026Review
- Screening and Evaluation of Salt-Tolerant Wheat Cultivars.Plants (Basel, Switzerland) · 2026Article
- The DoGST18-DoHSP70 module modulates the cadmium tolerance of Dendrobium officinale.BMC genomics · 2026Article
- Comparative genome-wide analysis in Setaria italica and Arabidopsis thaliana revealed functional conservation of specific FtsH proteases under high light and heat stress.Plant cell reports · 2026Article
- Overexpression of theFrontiers in genetics · 2026Article
- PtHSF5, a HSF transcription factor from Pinellia Ternata positively regulates heat tolerance in Arabidopsis.BMC plant biology · 2025Article
- Linking key genes to the stay-green phenotype for climate-smart Triticum aestivum L.BMC plant biology · 2025Article
- Impact of Temperature Stresses on Wheat Quality: A Focus on Starch and Protein Composition.Foods (Basel, Switzerland) · 2025Review
- Exploring associations between metabolites and gene transcripts of common bean (Phaseolus vulgaris L.) in response to rust (Uromyces appendiculatus) infection.BMC plant biology · 2025Article
- Enhancing wheat resilience: biotechnological advances in combating heat stress and environmental challenges.Plant molecular biology · 2025Review
- Heat shock factor ZmHsf17 positively regulates phosphatidic acid phosphohydrolase ZmPAH1 and enhances maize thermotolerance.Journal of experimental botany · 2025Article
- The Genetics and Breeding of Heat Stress Tolerance in Wheat: Advances and Prospects.Plants (Basel, Switzerland) · 2025Review
- Article
- Identification and mapping of QTLs and their corresponding candidate genes controlling high night-time temperature stress tolerance in wheat (Triticum aestivum L.).The plant genome · 2024Article
- ZmHsp18 screened from the ZmHsp20 gene family confers thermotolerance in maize.BMC plant biology · 2024Article
- Gene pyramiding for boosted plant growth and broad abiotic stress tolerance.Plant biotechnology journal · 2024Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Heat stress is a significant environmental factor adversely affecting crop yield. Crop adaptation to high-temperature environments requires transcriptional reprogramming of a suite of genes involved in heat stress protection. This study investigated the role of TaHsfA6f, a member of the A6 subclass of heat shock transcription factors, in the regulation of heat stress protection genes in Triticum aestivum (bread wheat), a poorly understood phenomenon in this crop species. Expression analysis showed that TaHsfA6f was expressed constitutively in green organs but was markedly up-regulated during heat stress. Overexpression of TaHsfA6f in transgenic wheat using a drought-inducible promoter resulted in up-regulation of heat shock proteins (HSPs) and a number of other heat stress protection genes that included some previously unknown Hsf target genes such as Golgi anti-apoptotic protein (GAAP) and the large isoform of Rubisco activase. Transgenic wheat plants overexpressing TaHsfA6f showed improved thermotolerance. Transactivation assays showed that TaHsfA6f activated the expression of reporter genes driven by the promoters of several HSP genes (TaHSP16.8, TaHSP17, TaHSP17.3, and TaHSP90.1-A1) as well as TaGAAP and TaRof1 (a co-chaperone) under non-stress conditions. DNA binding analysis revealed the presence of high-affinity TaHsfA6f-binding heat shock element-like motifs in the promoters of these six genes. Promoter truncation and mutagenesis analyses identified TaHsfA6f-binding elements that were responsible for transactivation of TaHSP90.1-A1 and TaGAAP by TaHsfA6f. These data suggest that TaHsfA6f is a transcriptional activator that directly regulates TaHSP, TaGAAP, and TaRof1 genes in wheat and its gene regulatory network has a positive impact on thermotolerance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.