ArticleGenetics2015
Evidence of natural selection acting on a polymorphic hybrid incompatibility locus in Mimulus.
Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- Postzygotic barriers persist despite ongoing introgression in hybridizing Mimulus species.Molecular ecology · 2024Article
- Genomics of plant speciation.Plant communications · 2023Review
- Stage-specific disruption of X chromosome expression during spermatogenesis in sterile house mouse hybrids.G3 (Bethesda, Md.) · 2022Article
- The hybrid lethality of interspecific FMolecular breeding : new strategies in plant improvement · 2022Review
- Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers.PLoS genetics · 2021Article
- The importance of intrinsic postzygotic barriers throughout the speciation process.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Loss of ecologically important genetic variation in late generation hybrids reveals links between adaptation and speciation.Evolution letters · 2020Article
- Rampant Misexpression in a Mimulus (Monkeyflower) Introgression Line Caused by Hybrid Sterility, Not Regulatory Divergence.Molecular biology and evolution · 2020Article
- A two-locus hybrid incompatibility is widespread, polymorphic, and active in natural populations of Mimulus.Evolution; international journal of organic evolution · 2018Article
- Article
- Gene duplicates cause hybrid lethality between sympatric species of Mimulus.PLoS genetics · 2018Article
- Mechanisms of Transmission Ratio Distortion at Hybrid Sterility Loci Within and BetweenG3 (Bethesda, Md.) · 2017Article
- Hybridization in Plants: Old Ideas, New Techniques.Plant physiology · 2017Review
- Selfish evolution of cytonuclear hybrid incompatibility in Mimulus.Proceedings. Biological sciences · 2016Article
- Evolution and Molecular Control of Hybrid Incompatibility in Plants.Frontiers in plant science · 2016Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
As a common cause of reproductive isolation in diverse taxa, hybrid incompatibilities are fundamentally important to speciation. A key question is which evolutionary forces drive the initial substitutions within species that lead to hybrid dysfunction. Previously, we discovered a simple genetic incompatibility that causes nearly complete male sterility and partial female sterility in hybrids between the two closely related yellow monkeyflower species Mimulus guttatus and M. nasutus. In this report, we fine map the two major incompatibility loci-hybrid male sterility 1 (hms1) and hybrid male sterility 2 (hms2)-to small nuclear genomic regions (each <70 kb) that include strong candidate genes. With this improved genetic resolution, we also investigate the evolutionary dynamics of hms1 in a natural population of M. guttatus known to be polymorphic at this locus. Using classical genetic crosses and population genomics, we show that a 320-kb region containing the hms1 incompatibility allele has risen to intermediate frequency in this population by strong natural selection. This finding provides direct evidence that natural selection within plant species can lead to hybrid dysfunction between species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.