ReviewComprehensive Physiology2014
Adrenal androgens and androgen precursors-definition, synthesis, regulation and physiologic actions.
Review in Comprehensive Physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.
- Anorexia nervosa and adrenal hormones: a systematic review and meta-analysis.European journal of endocrinology · 2023Pooled it
- 24-Hour Profiles of 11-Oxygenated CFrontiers in endocrinology · 2021Trial
- Testicular vs adrenal sources of hydroxy-androgens in prostate cancer.Endocrine-related cancer · 2017Trial
- Beyond androgen deprivation therapy: Next-generation hormonal therapies and emerging combination approaches in advanced prostate cancer.Urologic oncology · 2026Review
- Testosterone, cortisol, and fNIRS-based cortical activation associated with competitive task persistence and difficulty.Journal of neuroendocrinology · 2026Article
- High-speed resistance training vs. low-speed resistance training on body composition and physical function in adults with sarcopenic obesity.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- Androgen profiling in adolescent girls with polycystic ovary syndrome.Frontiers in endocrinology · 2026Article
- A retrospective study of severity-dependent HPG Axis suppression by glucocorticoids in Chinese women with Cushing syndrome.Frontiers in endocrinology · 2026Article
- Acute Adrenal Suppression Following Resistance Training in Elite Female Athletes: A Comprehensive Steroid Profile.Sports (Basel, Switzerland) · 2025Article
- Discovery and development of steroidal enzyme inhibitors as anti-cancer drugs: state-of-the-art and future perspectives.Journal of enzyme inhibition and medicinal chemistry · 2025Review
- Testosterone replacement therapy and spermatogenesis in reproductive age men.Nature reviews. Urology · 2025Review
- Androgens for genitourinary and vasomotor symptoms associated with menopause.The Cochrane database of systematic reviews · 2025Article
- Advancement in early diagnosis of polycystic ovary syndrome: biomarker-driven innovative diagnostic sensor.Mikrochimica acta · 2025Review
- Human Gonads Do Not Contribute to the Circulating Pool of 11-Oxygenated Androgens.The Journal of clinical endocrinology and metabolism · 2025Article
- Dog Neuter, Yes or No? A Summary of the Motivations, Benefits, and Harms, with Special Emphasis on the Behavioral Aspect.Animals : an open access journal from MDPI · 2025Review
- From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections.Reviews in endocrine & metabolic disorders · 2025Review
- The melanocortin receptor genes are linked to and associated with the risk of polycystic ovary syndrome in Italian families.Journal of ovarian research · 2024Article
- Impact of systemic treatments for advanced thyroid cancer on the adrenal cortex.European thyroid journal · 2024Article
- MicroRNA regulation of adrenal glucocorticoid and androgen biosynthesis.Vitamins and hormones · 2024Article
- Dose-Dependent Protective Effect of Hygrophila auriculata Seeds on Cyproterone Acetate-Induced Testicular Dysfunction.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The human adrenal produces more 19 carbon (C19) steroids, by mass, than either glucocorticoids or mineralocorticoids. However, the mechanisms regulating adrenal C19 steroid biosynthesis continue to represent one of the most intriguing mysteries of endocrine physiology. This review will discuss the C19 steroids synthesized by the human adrenal and the features within the adrenal that allow production of these steroids. Finally, we consider the effects of these steroids in normal physiology and disorders of adrenal C19 steroid excess.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.