Evidence map›Paper›PMID 25428613›Full record

ArticleScientific reports2014

IMP-1 encoded by a novel Tn402-like class 1 integron in clinical Achromobacter xylosoxidans, China.

Zhenhong Chen, Haihong Fang, Li Wang, Fengjun Sun, Yong Wang, Zhe Yin, Huiying Yang, Wenhui Yang, Jie Wang, Peiyuan Xia and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
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  7. Shigella flexneri: an emerging pathogen.Folia microbiologica · 2020
    Review
  8. Article
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  11. Article
  12. Sequencing ofFrontiers in cellular and infection microbiology · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Zhenhong ChenNanlou Respiratory Diseases Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Haihong FangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Li WangNanlou Respiratory Diseases Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Fengjun SunDepartment of Pharmacy, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
Yong WangInstitute of Disease Control and Prevention, Beijing 100071, China.
Zhe YinState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Huiying YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wenhui YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Jie WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Peiyuan XiaDepartment of Pharmacy, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
Dongsheng ZhouState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Changting LiuNanlou Respiratory Diseases Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Institute of Microbiology · CNArmy Medical University · CNChinese People's Liberation Army · CNPeople's Liberation Army No. 150 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achromobacter xylosoxidans strain A22732 is isolated from a pneumonia patient in China and produces carbapenemases OXA-114e and IMP-1, which are encoded by chromosome and plasmid, respectively, and confer resistance to multiple ß-lactam antibiotics including carbapenems. The blaIMP-1 gene together with aacA7 and orfE is captured by a novel Tn402-like class 1 integron in a conjugative IncP-1ß plasmid. In addition to the intrinsic integron promoter PcW, there is still a blaIMP-1 gene cassette-specific promoter. This is the first report of carbapenemase-encoding IncP-1ß plasmid in clinical bacterial isolate.

Indexed as

Achromobacter denitrificansBacterial Proteinsbeta-LactamasesCarbapenemsChinaChromosomesDNA Transposable ElementsDrug Resistance, Multiple, BacterialIntegronsMicrobial Sensitivity TestsPlasmidsPromoter Regions, GeneticBacterial Proteinsbeta-lactamase IMP-1beta-LactamasescarbapenemaseCarbapenemsDNA Transposable Elements

Identifiers

PMID25428613
PMCPMC4245530
OpenAlexW2083536583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.