Evidence map›Paper›PMID 25426945›Full record

ArticlePloS one2014

Deaths ascribed to non-communicable diseases among rural Kenyan adults are proportionately increasing: evidence from a health and demographic surveillance system, 2003-2010.

Penelope A Phillips-Howard, Kayla F Laserson, Nyaguara Amek, Caryl M Beynon, Sonia Y Angell, Sammy Khagayi, Peter Byass, Mary J Hamel, Anne M van Eijk, Emily Zielinski-Gutierrez and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 4 countries.

Penelope A Phillips-HowardDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Kayla F LasersonCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya; Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Nyaguara AmekCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Caryl M BeynonCenter for Public Health, Liverpool John Moores University, Liverpool, United Kingdom.
Sonia Y AngellDepartment of Non-Communicable Diseases, Division of Global Health Protection, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Sammy KhagayiCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Peter ByassUmeå Centre for Global Health Research, Umeå University, Umeå, Sweden.
Mary J HamelDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Anne M van EijkDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Emily Zielinski-GutierrezCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya; Division of Global HIV and AIDS, Centers for Disease Control and Prevention, Kisumu, Kenya.
Laurence SlutskerDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Kevin M De CockCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Center for Global Health, Centers for Disease Control and Prevention-Kenya, Nairobi, Kenya.
John VululeCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Frank O OdhiamboCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Kenya Medical Research Institute · KECenter for Global Health · USCenters for Disease Control and Prevention · USLiverpool School of Tropical Medicine · GBCenters for Disease Control and Prevention · KEDivision of Parasitic Diseases and Malaria · USLiverpool John Moores University · GBUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-communicable diseases (NCDs) result in more deaths globally than other causes. Monitoring systems require strengthening to attribute the NCD burden and deaths in low and middle-income countries (LMICs). Data from health and demographic surveillance systems (HDSS) can contribute towards this goal. METHODS AND

findingsBetween 2003 and 2010, 15,228 deaths in adults aged 15 years (y) and older were identified retrospectively using the HDSS census and verbal autopsy in rural western Kenya, attributed into broad categories using InterVA-4 computer algorithms; 37% were ascribed to NCDs, 60% to communicable diseases (CDs), 3% to injuries, and <1% maternal causes. Median age at death for NCDs was 66y and 71y for females and males, respectively, with 43% (39% male, 48% female) of NCD deaths occurring prematurely among adults aged below 65y. NCD deaths were mainly attributed to cancers (35%) and cardio-vascular diseases (CVDs; 29%). The proportionate mortality from NCDs rose from 35% in 2003 to 45% in 2010 (χ2 linear trend 93.4; p<0.001). While overall annual mortality rates (MRs) for NCDs fell, cancer-specific MRs rose from 200 to 262 per 100,000 population, mainly due to increasing deaths in adults aged 65y and older, and to respiratory neoplasms in all age groups. The substantial fall in CD MRs resulted in similar MRs for CDs and NCDs among all adult females by 2010. NCD MRs for adults aged 15y to <65y fell from 409 to 183 per 100,000 among females and from 517 to 283 per 100,000 population among males. NCD MRs were higher among males than females aged both below, and at or above, 65y.

conclusionsNCDs constitute a significant proportion of deaths in rural western Kenya. Evidence of the increasing contribution of NCDs to overall mortality supports international recommendations to introduce or enhance prevention, screening, diagnosis and treatment programmes in LMICs.

Indexed as

Cause of DeathAdolescentAdultAgedCardiovascular DiseasesCommunicable DiseasesData CollectionFemaleHumansKenyaKidney DiseasesLung DiseasesMaleMetabolic DiseasesMiddle AgedNeoplasms

Identifiers

PMID25426945
PMCPMC4245262
OpenAlexW2007972844

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.