Evidence map›Paper›PMID 25426888›Full record

ReviewBiomacromolecules2015

Opportunities for multicomponent hybrid hydrogels in biomedical applications.

Hang Kuen Lau, Kristi L Kiick

Abstract readReview
In one paragraph

Review in Biomacromolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Synergistic Dual Antibacterial Activity of Magnetite Hydrogels Doped with Silver.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hang Kuen LauDepartment of Materials Science and Engineering and ‡Biomedical Engineering, University of Delaware , Newark Delaware 19716, United States.
Kristi L Kiick

Funding

UDE COBRE: STRAINED MOLECULES FOR SYNTHESIS OF UNNATURAL AMINO ACIDSP20RR017716 · NCRR · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2002 to 2011
$16.9M
Highly resilient, hydrophilic bioelastomers for engineering vocal fold tissueR01DC011377 · NIDCD · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L · 2012 to 2016
$2.3M
Cell Instructive Materials For Engineering Vascular GraftsR01HL108110 · NHLBI · NEMOURS CHILDREN'S HOSPITAL, DELAWARE · PI AKINS, ROBERT E · 2013 to 2016
$1.4M
NCRR NIH HHS P20 RR017716NCRR NIH HHS P20-RR017716NHLBI NIH HHS R01 HL108110NHLBI NIH HHS R01-HL108110NIDCD NIH HHS R01 DC011377NIDCD NIH HHS R01-DC011377A
6 · The paper itself

Abstract

Hydrogels provide mechanical support and a hydrated environment that offer good cytocompatibility and controlled release of molecules, and myriad hydrogels thus have been studied for biomedical applications. In the past few decades, research in these areas has shifted increasingly to multicomponent hydrogels that better capture the multifunctional nature of native biological environments and that offer opportunities to selectively tailor materials properties. This review summarizes recent approaches aimed at producing multicomponent hydrogels, with descriptions of contemporary chemical and physical approaches for forming networks, and of the use of both synthetic and biologically derived molecules to impart desired properties. Specific multicomponent materials with enhanced mechanical properties are presented, as well as materials in which multiple biological functions are imparted for applications in tissue engineering, cancer treatment, and gene therapies. The progress in the field suggests significant promise for these approaches in the development of biomedically relevant materials.

Indexed as

AnimalsBiocompatible MaterialsBiomedical TechnologyClick ChemistryDrug Delivery SystemsHumansHydrogelsTissue EngineeringBiocompatible MaterialsHydrogels

Identifiers

PMID25426888
PMCPMC4294583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.