Evidence map›Paper›PMID 25426330›Full record

ArticleBiomedical optics express2014

Modified Beer-Lambert law for blood flow.

Wesley B Baker, Ashwin B Parthasarathy, David R Busch, Rickson C Mesquita, Joel H Greenberg, A G Yodh

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 277 citations in OpenAlex.

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  6. Cerebral Blood Flow Response During Bolus Normal Saline Infusion After Ischemic Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2019
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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Wesley B BakerDept. Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ashwin B ParthasarathyDept. Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
David R BuschDept. Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA ; Div. of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Rickson C MesquitaInstitute of Physics, University of Campinas, Campinas, SP 13083-859, Brazil.
Joel H GreenbergDept. Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.
A G YodhDept. Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Pennsylvania · USUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Training in Molecular Therapeutics for Pediatric CardiologyT32HL007915 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Robert J Levy, JOSEPH W ROSSANO · 1999 to 2026
$13.4M
Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
Diffuse Optics for Acute Stroke ManagementR01NS060653 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI YODH, ARJUN G. · 2008 to 2018
$5.5M
Augmented Physiologic Monitoring to Predict Brain Injury in Infants with CHDR01NS072338 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI LICHT, DANIEL JACQUES · 2011 to 2015
$1.7M
NHLBI NIH HHS T32 HL007915NIBIB NIH HHS P41 EB015893NINDS NIH HHS R01 NS060653NINDS NIH HHS R01 NS072338
6 · The paper itself

Abstract

We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements. The new formulation enables blood flow monitoring from temporal intensity autocorrelation function data taken at single or multiple delay-times. Consequentially, the speed of the optical blood flow measurement can be substantially increased. The scheme facilitates blood flow monitoring of highly scattering tissues in geometries wherein light propagation is diffusive or non-diffusive, and it is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues.

Indexed as

(110.4153) Motion estimation and optical flow(170.1470) Blood or tissue constituent monitoring(170.1610) Clinical applications(170.2655) Functional monitoring and imaging(170.3660) Light propagation in tissues(170.3880) Medical and biological imaging(170.5270) Photon density waves(170.6480) Spectroscopy, speckle(170.6510) Spectroscopy, tissue diagnostics(290.4210) Multiple scattering

Identifiers

PMID25426330
PMCPMC4242038
OpenAlexW2016895538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.