ArticleBiomedical optics express2014
Laser induced breakdown spectroscopy for bone and cartilage differentiation - ex vivo study as a prospect for a laser surgery feedback mechanism.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Influence of Sample Preparation Methods for Porcine Tissue: Calibration-Free LIBS for In Vivo Applications.Journal of biophotonics · 2026Article
- Analysis of femoroacetabular impingement by a triade of label-free optical spectroscopy techniques.Communications biology · 2025Article
- Assessment of the Electrolyte Heterogeneity of Tissues in Mandibular Bone-Infiltrating Head and Neck Cancer Using Laser-Induced Breakdown Spectroscopy.International journal of molecular sciences · 2024Article
- The role of potassium in depth profiling of the tumor border in bone-invasive oral cancer using laser-induced breakdown spectroscopy (LIBS): a pilot study.Journal of cancer research and clinical oncology · 2023Article
- Quantitative elemental mapping of biological tissues by laser-induced breakdown spectroscopy using matrix recognition.Scientific reports · 2023Article
- Real-time closed-loop tissue-specific laser osteotomy using deep-learning-assisted optical coherence tomography.Biomedical optics express · 2023Article
- Evaluation of electrolyte element composition in human tissue by laser-induced breakdown spectroscopy (LIBS).Scientific reports · 2022Article
- Methodology for the Implementation of Internal Standard to Laser-Induced Breakdown Spectroscopy Analysis of Soft Tissues.Sensors (Basel, Switzerland) · 2021Article
- Combined Nd:YAG and Er:YAG lasers for real-time closed-loop tissue-specific laser osteotomy.Biomedical optics express · 2020Article
- Remote photoacoustic sensing using speckle-analysis.Scientific reports · 2019Article
- Elemental analysis of tissue pellets for the differentiation of epidermal lesion and normal skin by laser-induced breakdown spectroscopy.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laser surgery enables for very accurate, fast and clean modeling of tissue. The specific and controlled cutting and ablation of tissue, however, remains a central challenge in the field of clinical laser applications. The lack of information on what kind of tissue is being ablated at the bottom of the cut may lead to iatrogenic damage of structures that were meant to be preserved. One such example is the shaping or removal of diseased cartilaginous and bone tissue in the temporomandibular joint (TMJ). Diseases of the TMJ can induce deformation and perforation of the cartilaginous discus articularis, as well as alterations to the cartilaginous surface of the condyle or even the bone itself. This may result in restrictions of movement and pain. The aim of a surgical intervention ranges from specific ablation and shaping of diseased cartilage, bone or synovial tissues to extensive removal of TMJ structures. One approach to differentiate between these tissues is to use Laser Induced Breakdown Spectroscopy (LIBS). The ultimate goal is a LIBS guided feedback control system for surgical laser systems that enables real-time tissue identification for tissue specific ablation. In the presented study, the authors focused on the LIBS based differentiation between cartilage tissue and cortical bone tissue using an ex-vivo pig model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.