Evidence map›Paper›PMID 25426227›Full record

ArticleJournal of radiology case reports2014

Long-term lumbar multifidus muscle atrophy changes documented with magnetic resonance imaging: a case series.

Mark Woodham, Andrew Woodham, Joseph G Skeate, Michael Freeman

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of radiology case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mark WoodhamPrivate Practice, Tacoma, Washington, USA.
Andrew WoodhamDepartment of Genetics Molecular and Cellular Biology, University of Southern California, Los Angeles, California, USA.
Joseph G SkeateDepartment of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, California, USA.
Michael FreemanDepartment of Public Health and Preventive Medicine, Oregon Health and Science University School of Medicine, Portland, Oregon, USA.
Oregon Health & Science University · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective case series of three patients with chronic low back pain who received baseline MRI scans revealing multifidus muscle atrophy with fatty replacement is provided. Each patient received spinal manipulative therapy, and two were compliant with low back exercises targeting the multifidus. A follow-up scan performed >1 year later was compared to the baseline scan revealing a decrease in atrophy with fatty replacement in the two patients who performed multifidus-focused low back exercises (15% and 39% on the left and 7% and 32% on the right respectively), and an increase in the patient who underwent spinal manipulation alone (41% and 53%). Interestingly, the decrease in atrophy in the two patients that performed the exercises correlated to functional improvements. Though limited, these results highlight the utility of MRI in quantifying positive and negative long-term changes in multifidus atrophy, which may be an indicator of recovery in chronic low back pain patients.

Indexed as

Magnetic Resonance ImagingAdultFollow-Up StudiesHumansLow Back PainMaleMuscular AtrophyMusculoskeletal ManipulationsOccupational DiseasesParaspinal MusclesPilot ProjectsRecovery of FunctionRetrospective Studieschronic low back painLumbar multifidus musclelumbar multifidus muscle atrophyMRImultifidi

Identifiers

PMID25426227
PMCPMC4242062
OpenAlexW2027802183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.