ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014
Recruitment and retention of pregnant women into clinical research trials: an overview of challenges, facilitators, and best practices.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Participation of Women in Cardiovascular Trials From 2017 to 2023: A Systematic Review.JAMA network open · 2025Pooled it
- Understanding Sociodemographic Disparities in Maternal-Fetal Surgery Study Participation.Fetal diagnosis and therapy · 2022Pooled it
- A Systematic Review of Technology-Based Prevention and Treatment Interventions for Perinatal Depression and Anxiety in Latina and African American Women.Maternal and child health journal · 2021Pooled it
- Effectiveness and safety of herbal medicines for induction of labour: a systematic review and meta-analysis.BMJ open · 2018Pooled it
- A systematic review of components of community-based organisation engagement.Health & social care in the community · 2018Pooled it
- The acceptability and feasibility of a randomised controlled trial of serial prophylactic exchange blood transfusion versus usual care in pregnant women with sickle cell disease: a qualitative study.BMC pregnancy and childbirth · 2026Trial
- Feasibility and Preliminary Efficacy of Enhanced Midwifery Care to Support Women Experiencing Subclinical Depression: A Pilot Randomised Controlled Trial.International journal of environmental research and public health · 2025Trial
- Glucocorticoids after birth trauma and the associated risk of developing posttraumatic stress disorder: a non-randomized open-label pilot trial.Frontiers in global women's health · 2025Trial
- Feasibility Study ofNutrients · 2023Trial
- The gestational diabetes future diabetes prevention study (GODDESS): A partially randomised feasibility controlled trial.PloS one · 2022Trial
- Trial
- Probiotics as a treatment for prenatal maternal anxiety and depression: a double-blind randomized pilot trial.Scientific reports · 2021Trial
- Factors associated with referring close contacts to an app with individually-tailored vaccine information.Vaccine · 2020Trial
- Group Prenatal Care Attendance and Women's Characteristics Associated with Low Attendance: Results from Centering and Racial Disparities (CRADLE Study).Maternal and child health journal · 2019Trial
- Trial
- Recruiting pregnant smokers from Text4baby for a randomized controlled trial of Quit4baby.Translational behavioral medicine · 2017Trial
- How to Efficiently Recruit Participants in a Perinatal Cohort Study: CAN-B Cohort Strategies/Lessons Learned.Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2026Article
- Article
- Recruitment of healthy third-trimester pregnant women and their newborns into a prospective dental study at a primary health care clinic.BMC pregnancy and childbirth · 2026Article
- Salivary cortisol reactivity to stress in pregnancy: A scoping review.Psychoneuroendocrinology · 2026Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnant women are a vulnerable group who are needed in clinical research studies to advance prevention and treatment options for this population. Yet, pregnant women remain underrepresented in clinical research. Through the lens of the socioecological model, we highlight reported barriers and facilitators to recruitment and retention of pregnant women in studies that sought their participation. We trace historical, policy-based reasons for the exclusion of pregnant women in clinical studies to present-day rationale for inclusion of this group. The findings highlight why it has been difficult to recruit and retain this population over time. A body of literature suggests that integrative sampling and recruitment methods that leverage the influence and reach of prenatal providers will overcome recruitment challenges. We argue that these strategies, in combination with building strong engagement with existing community-based organizations, will enable teams to more effectively promote and retain pregnant women in future longitudinal cohort studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.