Evidence map›Paper›PMID 25425684›Full record

Trial reportHaematologica2015

Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma.

Kevin W Song, Meletios A Dimopoulos, Katja C Weisel, Philippe Moreau, Antonio Palumbo, Andrew Belch, Stephen Schey, Pieter Sonneveld, Lars Sternas, Xin Yu and 5 more

Abstract readComparative StudyLetterRandomized Controlled Trial
In one paragraph

Trial report in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Patient-reported outcomes in relapsed/refractory multiple myeloma: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Health-related quality of life of carfilzomib- and daratumumab-based therapies in patients with relapsed/refractory multiple myeloma, based on German benefit assessment data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  9. Review
  10. Pomalidomide-Induced Pulmonary Toxicity in Multiple Myeloma.The American journal of the medical sciences · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kevin W SongVancouver General Hospital, BC, Canada ksong@bccancer.bc.ca.
Meletios A DimopoulosAlexandra Hospital, Athens, Greece.
Katja C WeiselUniversity Hospital Tübingen, Germany.
Philippe MoreauUniversity Hospital Hotel-Dieu, Nantes, France.
Antonio PalumboUniversity Hospital and Health City of Science of Torino, Italy.
Andrew BelchUniversity of Alberta, Edmonton, Canada.
Stephen ScheyKing's College Hospital and King's College London, UK.
Pieter SonneveldErasmus Medical Center Rotterdam, The Netherlands.
Lars SternasCelgene Corporation, Summit, NJ, USA.
Xin YuCelgene Corporation, Summit, NJ, USA.
Ramesh AmatyaAdelphi Values, Boston, MA, USA.
Mara S MonziniCelgene Corporation, Summit, NJ, USA.
Mohamed ZakiCelgene Corporation, Summit, NJ, USA.
Christian JacquesCelgene Corporation, Summit, NJ, USA.
Jesus San MiguelHospital Universitario de Salamanca, Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quality of LifeAntineoplastic Combined Chemotherapy ProtocolsCross-Sectional StudiesDexamethasoneDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedMultiple MyelomaNeoplasm Recurrence, LocalNeoplasm StagingPrognosisThalidomideDexamethasonepomalidomideThalidomidemultiple myelomaPomalidomidequality of life

Identifiers

PMID25425684
PMCPMC4803120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.