Evidence map›Paper›PMID 25425258›Full record

ArticleEuropean journal of applied physiology2015

Intramuscular determinants of the ability to recover work capacity above critical power.

Philip Friere Skiba, Jonathan Fulford, David C Clarke, Anni Vanhatalo, Andrew M Jones

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Article in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  5. Article
  6. Is there a critical rate of torque development?European journal of applied physiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Bi-exponential modelling ofEuropean journal of applied physiology · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip Friere SkibaSchool of Sport and Health Sciences, St. Luke's Campus, University of Exeter, Heavitree Road, Exeter, Devon, EX1 2LU, UK, philip.skiba@advocatehealth.com.
Jonathan Fulford
David C Clarke
Anni Vanhatalo
Andrew M Jones

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe primary purpose of this investigation was to compare the recovery of the W' to the recovery of intramuscular substrates and metabolites using (31)P- and (1)H-magnetic resonance spectroscopy.

methodsTen healthy recreationally trained subjects were tested to determine critical power (CP) and W' for single-leg-extensor exercise. They subsequently exercised in the bore of a 1.5-T MRI scanner at a supra-CP work rate. Following exhaustion, the subjects rested in place for 1, 2, 5 or 7 min, and then repeated the effort. The temporal course of W' recovery was estimated, which was then compared to the recovery of creatine phosphate [PCr], pH, carnosine content, and to the output of a novel derivation of the W' BAL model.

resultsW' recovery closely correlated with the predictions of the novel model (r = 0.97, p = 0.03). [PCr] recovered faster [Formula: see text] than W' [Formula: see text] The W' available for the second exercise bout was directly correlated with the difference between [PCr] at the beginning of the work bout and [PCr] at exhaustion (r = 0.99, p = 0.005). Nonlinear regression revealed an inverse curvilinear relationship between carnosine concentration and the W' t 1/2 (r (2) = 0.55).

conclusionThe kinetics of W' recovery in single-leg-extensor exercise is comparable to that observed in whole-body exercise, suggesting a conserved mechanism. The extent to which the recovery of the W' can be directly attributed to the recovery of [PCr] is unclear. The relationship of the W' to muscle carnosine content suggests novel future avenues of investigation.

Indexed as

Physical EnduranceAdultCarnosineFemaleHumansMaleModels, BiologicalMuscle, SkeletalPhosphocreatineCarnosinePhosphocreatine

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.