Evidence map›Paper›PMID 25425197›Full record

ArticleLeukemia2015

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.

F De Falco, R Sabatini, F Falzetti, M Di Ianni, P Sportoletti, S Baldoni, B Del Papa, I Screpanti, P Marconi, E Rosati

Open access · bronzeAbstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

F De FalcoDepartment of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
R SabatiniDepartment of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
F FalzettiDepartment of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
M Di IanniDepartment of Life, Health and Environmental Sciences, Hematology Section, University of L'Aquila, L'Aquila, Italy.
P SportolettiDepartment of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
S BaldoniDepartment of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
B Del PapaDepartment of Medicine, Hematology and Clinical Immunology Section, University of Perugia, Perugia, Italy.
I ScrepantiDepartment of Molecular Medicine, University La Sapienza, Rome, Italy.
P MarconiDepartment of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
E RosatiDepartment of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.
University of Perugia · ITSapienza University of Rome · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, LeukemicMutationAllelesCasein Kinase IIGene FrequencyGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaHumansLeukemia, Lymphocytic, Chronic, B-CellPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsPhosphorylationProtein Kinase InhibitorsProtein Structure, TertiaryProto-Oncogene Proteins c-aktReceptor, Notch1Casein Kinase IIGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaNOTCH1 protein, humanPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsProtein Kinase InhibitorsProto-Oncogene Proteins c-aktReceptor, Notch1

Identifiers

PMID25425197
OpenAlexW2084225236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.