ArticleInternational journal of legal medicine2015
Assessing product adulteration in natural health products for laxative yielding plants, Cassia, Senna, and Chamaecrista, in Southern India using DNA barcoding.
Article in International journal of legal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Skeletons in the closet? Using a bibliometric lens to visualise phytochemical and pharmacological activities linked toFrontiers in plant science · 2024Pooled it
- Molecular docking analysis of IL-6 and TNF-alpha with phytochemicals fromBioinformation · 2025Article
- Existing status and future advancements of adulteration detection techniques in herbal products.Molecular biology reports · 2024Review
- Comprehensive analysis using DNA metabarcoding, SCAR marker based PCR assay, and HPLC unveils the adulteration in Brahmi herbal products.Molecular biology reports · 2023Article
- Bioherbicidal Activity and Metabolic Profiling of Allelopathic Metabolites of Three Cassia species using UPLC-qTOF-MS/MS and Molecular Networking.Metabolomics : Official journal of the Metabolomic Society · 2023Article
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- Horizon scan of DNA-based methods for quality control and monitoring of herbal preparations.Frontiers in pharmacology · 2023Review
- Essential Oil Chemotypes and Genetic Variability ofMolecules (Basel, Switzerland) · 2022Article
- A Review on Application of DNA Barcoding Technology for Rapid Molecular Diagnostics of Adulterants in Herbal Medicine.Drug safety · 2022Review
- Advancements and future prospective of DNA barcodes in the herbal drug industry.Frontiers in pharmacology · 2022Review
- rbcL, a potential candidate DNA barcode loci for aconites: conservation of himalayan aconites.Molecular biology reports · 2021Article
- The efficacy of machine learning algorithm for raw drug authentication inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Pitfalls and promises of raw drug identification techniques in the ayurvedic industry: an overview.3 Biotech · 2020Review
- Assessing the Identity of Commercial Herbs From a Cambodian Market Using DNA Barcoding.Frontiers in pharmacology · 2020Article
- A Simple, Rapid, and Practical Method for DistinguishingMolecules (Basel, Switzerland) · 2019Article
- Article
- Comparative metabolome-based classification of Senna drugs: a prospect for phyto-equivalency of its different commercial products.Metabolomics : Official journal of the Metabolomic Society · 2019Article
- DNA Metabarcoding Authentication of Ayurvedic Herbal Products on the European Market Raises Concerns of Quality and Fidelity.Frontiers in plant science · 2019Article
- Mitigating the Impact of Admixtures in Thai Herbal Products.Frontiers in pharmacology · 2019Review
- Antioxidant and anticancer activities of Trigonella foenum-graecum, Cassia acutifolia and Rhazya stricta.BMC complementary and alternative medicine · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medicinal plants such as Cassia, Senna, and Chamaecrista (belonging to the family Fabaceae) are well known for their laxative properties. They are extensively used within indigenous health care systems in India and several other countries. India exports over 5000 metric tonnes per year of these specific herbal products, and the demand for natural health product market is growing at approximately 10-15% annually. The raw plant material used as active ingredients is almost exclusively sourced from wild populations. Consequently, it is widely suspected that the commercial herbal products claiming to contain these species may be adulterated or contaminated. In this study, we have attempted to assess product authentication and the extent of adulteration in the herbal trade of these species using DNA barcoding. Our method includes four common DNA barcode regions: ITS, matK, rbcL, and psbA-trnH. Analysis of market samples revealed considerable adulteration of herbal products: 50% in the case of Senna auriculata, 37% in Senna tora, and 8% in Senna alexandrina. All herbal products containing Cassia fistula were authentic, while the species under the genus Chamaecrista were not in trade. Our results confirm the suspicion that there is rampant herbal product adulteration in Indian markets. DNA barcodes such as that demonstrated in this study could be effectively used as a regulatory tool to control the adulteration of herbal products and contribute to restoring quality assurance and consumer confidence in natural health products.
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