Evidence map›Paper›PMID 25424798›Full record

ArticleHuman vaccines & immunotherapeutics2014

Engineered PRINT(®) nanoparticles for controlled delivery of antigens and immunostimulants.

Anton Beletskii, Ashley Galloway, Shyam Rele, Michele Stone, Frank Malinoski

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anton Beletskiia Liquidia Technologies; Research Triangle Park, NC USA.
Ashley Galloway
Shyam Rele
Michele Stone
Frank Malinoski

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particle replication in non-wetting templates (PRINT) is a novel nanoparticle platform that provides compositional flexibility with the ability to specify size and shape in formulating vaccines. The PRINT platform also offers manufacturing and cost advantages over traditional particle technologies. Across multiple antigen and adjuvant formulations, robust antibody and cellular responses have been achieved using PRINT particles in mouse models. Preclinical studies applying PRINT technology in the disease areas of influenza, malaria, and pneumonia are described in this commentary. The proof of principle studies pave the way toward significant cost-effective solutions to global vaccine supply needs.

Indexed as

Adjuvants, ImmunologicAnimalsAntigensDrug CarriersDrug Evaluation, PreclinicalHumansInfluenza, HumanMalariaNanoparticlesNanotechnologyPneumoniaAdjuvants, ImmunologicAntigensDrug Carriersadjuvantantigen deliveryconjugate vaccinenanoparticlenanotechnologyvaccine

Identifiers

PMID25424798
PMCPMC4186044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.