Evidence map›Paper›PMID 25424502›Full record

ArticleLipids in health and disease2014

Energy replacement using glucose does not increase postprandial lipemia after moderate intensity exercise.

Chih-Hui Chiu, Stephen Francis Burns, Tsung-Jen Yang, Yi-Hsin Chang, Yi-Liang Chen, Cheng-Kang Chang, Ching-Lin Wu

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Chih-Hui Chiu
Stephen Francis Burns
Tsung-Jen Yang
Yi-Hsin Chang
Yi-Liang Chen
Cheng-Kang Chang
Ching-Lin WuGraduate Institute of Sports and Health Management, National Chung Hsing University, Taichung, Taiwan. psclw@dragon.nchu.edu.tw.
National Taiwan University of Sport · TWNanyang Technological University · SGNational Chung Hsing University · TWNational Taiwan Normal University · TWUniversity of Taipei · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAerobic exercise can decrease postprandial triglyceride (TG) concentrations but the relationship between exercise-induced energy deficits and postprandial lipemia is still unclear. The aim of the present study was to examine the effect of a single bout of aerobic exercise, with and without energy replacement, on postprandial lipemia and on peripheral blood mononuclear cell (PBMC) mRNA expression of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) receptors and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR).

methodsNine healthy male humans completed three two-day trials in a random order. On day 1, volunteers rested (CON), completed 60 minutes of treadmill walking at 50% of VO2peak (EX) or completed the same bout of walking but with the energy replaced afterwards with a glucose solution (EXG). On day 2, volunteers rested and consumed a high fat test meal in the morning.

resultsTotal and incremental TG AUC were significantly lower on the EXG (P < 0.05) and EX (P < 0.05) trials than the CON trial with no difference between the two exercise trials. No significant difference was observed in VLDL or LDL receptor mRNA expression among the trials (P > 0.05).

conclusionsIn conclusion, energy replacement by glucose did not affect the decrease in postprandial TG concentrations observed after moderate intensity exercise and exercise does not affect changes in PBMC HMGCR, VLDL and LDL receptor mRNA expression.

Indexed as

Area Under CurveCholesterol, HDLEnergy MetabolismFatty Acids, NonesterifiedGene ExpressionGlucoseHumansHydroxymethylglutaryl CoA ReductasesLeukocytes, MononuclearMalePhysical ExertionPostprandial PeriodReceptors, LDLTriglyceridesWalkingYoung AdultCholesterol, HDLFatty Acids, NonesterifiedGlucoseHMGCR protein, humanHydroxymethylglutaryl CoA ReductasesReceptors, LDLTriglyceridesVLDL receptor

Identifiers

PMID25424502
PMCPMC4258013
OpenAlexW2123498654

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.