ArticleRheumatology international2015
Determinants of medication non-adherence in Egyptian patients with systemic lupus erythematosus: Sharkia Governorate.
Article in Rheumatology international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- A systematic review of the barriers affecting medication adherence in patients with rheumatic diseases.Rheumatology international · 2017Pooled it
- Polypharmacy in Adults With Systemic Lupus Erythematosus.Arthritis care & research · 2026Article
- Adherence to oral and topical medications among dermatology patients.Archives of dermatological research · 2025Article
- Medication-related hospitalisations in patients with SLE.Lupus science & medicine · 2025Article
- Article
- Cognitive dysfunction in patients with childhood-onset systemic lupus erythematosus may impact treatment.Advances in rheumatology (London, England) · 2023Article
- Annual Direct Cost and Cost-Drivers of Systemic Lupus Erythematosus: A Multi-Center Cross-Sectional Study from CSTAR Registry.International journal of environmental research and public health · 2023Article
- Medication Non-Adherence in Rheumatology, Oncology and Cardiology: A Review of the Literature of Risk Factors and Potential Interventions.International journal of environmental research and public health · 2022Review
- How Can We Enhance Adherence to Medications in Patients with Systemic Lupus Erythematosus? Results from a Qualitative Study.Journal of clinical medicine · 2022Article
- Medication adherence in systemic lupus erythematosus during Brazilian COVID-19 pandemic.Lupus · 2022Article
- Barriers to medication adherence and degree of nonadherence in a systemic lupus erythematosus (SLE) outpatient population.Rheumatology international · 2021Observational
- Effective factors in non-compliance with therapeutic orders of specialists in outpatient clinics in Iran: a qualitative study.BMC health services research · 2019Article
- Rheumatology in Egypt: back to the future.Rheumatology international · 2019Review
- Depressive Symptoms Are Associated With Low Treatment Adherence in African American Individuals With Systemic Lupus Erythematosus.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2018Article
- Article
- Predictors of medication nonadherence in patients with systemic lupus erythematosus in Sichuan: a cross-sectional study.Patient preference and adherence · 2018Article
- Medication adherence and persistence in patients with autoimmune rheumatic diseases: a narrative review.Patient preference and adherence · 2018Review
- The Duality of Economic Issues With Medication Non-adherence in Patients With Inflammatory Arthritis.Current rheumatology reports · 2017Review
- The rate of adherence to urate-lowering therapy and associated factors in Chinese gout patients: a cross-sectional study.Rheumatology international · 2017Article
- Adherence to Oral and Topical Medications in Cutaneous Lupus Erythematosus is not Well Characterized.Dermatology and therapy · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to identify the determinants of adherence to medication among Egyptian patients with SLE. A single-center cross-sectional study was conducted among Egyptian patients with SLE. Adherence to medication was measured via The Compliance Questionnaire for Rheumatology-19, and the patients were classified as non-adherers if they were taking <80% of their medication correctly. Predictors of adherence to SLE medication were determined by multiple logistic regressions. The mean age of participants was 30.9 ± 11.7 years. Females constituted 95% of all participants. Thirty-eight (%) were taking <80% of their medication correctly. On logistic regression analysis, the significant independent predictors of medication non-adherence were lower educational level (OR 5.6, 95% CI 2.1-7.3, P < 0.001), very low and low socioeconomic status (OR 2.6, 95% CI 1.6-4.3, P < 0.04), rural residency (OR 3.4, 95% CI 1.4-5, P < 0.01), more number of medications (OR 3.2, 95% CI 2.3-6.9, P < 0.01), and higher depressive symptoms (OR 3.7, 95% CI 1.4-10.2, P < 0.001). The adherence rate reported in this study was quite low. Appropriate adherence enhancing intervention strategies targeted at reducing pill load, minimizing depressive symptoms, and ensuring an uninterrupted access to free services regimen for patients with low socioeconomic status is strongly recommended. More attention should be given to SLE patients who live in rural regions.
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