SynthesisSurgical endoscopy2015
Safety of transvaginal hybrid NOTES cholecystectomy: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03921502 (Randomized Multicentre Double-blind Clinical Trial Comparing ERCP vs ERCP and Transmural Gall Bladder Drainage in Non-surgical Patients With Symptomatic Choledocholithiasis), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Multicentre Double-blind Clinical Trial Comparing ERCP vs ERCP and Transmural Gall Bladder Drainage in Non-surgical Patients With Symptomatic Choledocholithiasis
Who cites it
19 citing papers in PubMed.
- Minimally Invasive Surgical Techniques in the Treatment of Appendicitis: A Narrative Review.Cureus · 2025Review
- Research progress in the treatment of gallstones with laparoscopic and endoscopic surgery: a narrative review.BMC surgery · 2025Review
- Evolution of minimally invasive cholecystectomy: a narrative review.BMC surgery · 2024Review
- An Observational Study Comparing Hybrid Transvaginal Notes and Four-Port Laparoscopic Cholecystectomy.Cureus · 2023Article
- [Clinical value of alternative technologies to standard laparoscopic cholecystectomy - single port, reduced port, robotics, NOTES].Chirurgie (Heidelberg, Germany) · 2022Review
- A snare-assisted pure NOTES retrograde cholecystectomy using a single channel flexible endoscope: a pilot experiment in a porcine model.Surgical endoscopy · 2020Article
- Does obesity influence the results in Transvaginal Hybrid-NOTES cholecystectomy?Surgical endoscopy · 2018Article
- Less pain after transvaginal cholecystectomy: single-center pooled analysis.Surgical endoscopy · 2017Article
- [Implementation of hybrid-NOTES sigmoidectomy for diverticular disease : In a center for minimally invasive surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017Article
- Feasibility and Technique for Transvaginal Natural Orifice Transluminal Endoscopic Surgery Liver Resection: A Porcine Model.Surgical laparoscopy, endoscopy & percutaneous techniques · 2017Article
- Laparoscopic Gastrectomy and Transvaginal Specimen Extraction in a Morbidly Obese Patient with Gastric Cancer.Journal of gastric cancer · 2016Article
- Natural Orifice Translumenal Endoscopic Surgery: Review of Its Applications in Bariatric Procedures.Obesity surgery · 2016Review
- Transvaginal Hybrid NOTES Procedure for Treatment of Gallstone Ileus.Case reports in surgery · 2016Article
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
- New minimally invasive approaches for cholecystectomy: Review of literature.World journal of gastrointestinal surgery · 2015Review
- Transvaginal Mini-Laparoscopic Splenectomy.Cureus · 2015Article
- Laparoscopic-Assisted Transvaginal Cholecystectomy - the US Military Experience With Long-Term Follow Up.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
- Hybrid Transvaginal NOTES and Mini-Laparoscopic Colectomy: Benefit Through Synergy.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
- EUS-guided gallbladder drainage: Current status and future prospects.Endoscopic ultrasoundArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundDespite increasing data regarding clinical outcomes following transvaginal hybrid NOTES cholecystectomy (TVC), a consensus regarding safety based on comparative studies has yet to be reached. The aim of this systematic review and meta-analysis was to compare safety and clinical outcomes of TVC with conventional laparoscopic cholecystectomy (CLC) for the treatment of benign gallstone disease.
methodsA comprehensive search for published studies comparing TVC and CLC was performed. Review of each study was conducted and data were extracted. All pooled outcome measures were determined using random-effects models.
resultsData were retrieved from 14 studies describing 1,145 patients. There was no difference in total complications (POR = 0.68; 95 % CI 0.40-1.14; P = 0.14), incidence of bile duct injury (POR = 1.33; 95 % CI 0.31-5.66; P = 0.70), Clavien-Dindo Grade II (POR = 0.48; 95 % CI 0.14-1.60; P = 0.23) or Grade III (POR = 0.63; 95 % CI 0.24-1.65; P = 0.34) complications between TCV and CLC. Time of return to normal activities was significantly reduced in the TVC group (WMD = -4.86 days; 95 % CI -9.33 to -0.39; P = 0.03), and there was a non-significant reduction in postoperative pain on days 1 (WMD = -0.80; 95 % CI -1.60 to 0.01; P = 0.05) and 3 (WMD = -0.89; 95 % CI -1.77 to -0.01; P = 0.05).
conclusionsTVC is safe when performed by appropriately trained surgeons and may be associated with a faster return to normal activities and decreased postoperative pain.
Indexed as
Identifiers
25424364What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.