ArticleMolecular plant-microbe interactions : MPMI2015
Hydroxycinnamic Acid Degradation, a Broadly Conserved Trait, Protects Ralstonia solanacearum from Chemical Plant Defenses and Contributes to Root Colonization and Virulence.
Article in Molecular plant-microbe interactions : MPMI, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 75 citations in OpenAlex.
- A genome-scale metabolic model of a pathosystem sheds light on bacterial wilt.Plant physiology · 2026Article
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- Metabolomic and Genomic Analysis of Bioactive Compounds of Phacidium infestans Karsten DSM 5139 Cultivated on Pinus sylvestris Needles.Environmental microbiology reports · 2025Article
- Antibacterial Activity and Mechanism of Three Root Exudates from Mulberry Seedlings againstPlants (Basel, Switzerland) · 2024Article
- MarR Family Transcriptional Regulators and Their Roles in Plant-Interacting Bacteria.Microorganisms · 2023Review
- Plant-PathogenicmBio · 2023Article
- An MKP-MAPK protein phosphorylation cascade controls vascular immunity in plants.Science advances · 2022Article
- The Role of Hydroxycinnamic Acid Amide Pathway in Plant Immunity.Frontiers in plant science · 2022Review
- Trehalose increases tomato drought tolerance, induces defenses, and increases resistance to bacterial wilt disease.PloS one · 2022Article
- UV-B light and its application potential to reduce disease and pest incidence in crops.Horticulture research · 2021Review
- Convergent Rewiring of the Virulence Regulatory Network Promotes Adaptation of Ralstonia solanacearum on Resistant Tomato.Molecular biology and evolution · 2021Article
- Partial purification and characterization of 2, 4-diacetylphloroglucinol producingSaudi journal of biological sciences · 2021Article
- Metabolomic Evaluation ofFrontiers in plant science · 2021Article
- Caffeic Acid in Tobacco Root Exudate Defends Tobacco Plants From Infection byFrontiers in plant science · 2021Article
- Metabolic Profiling of Resistant and Susceptible Tobaccos Response Incited byFrontiers in plant science · 2021Article
- Grapevine phenolic compounds influence cell surface adhesion of Xylella fastidiosa and bind to lipopolysaccharide.PloS one · 2020Article
- Involvement of a PadR regulator PrhP on virulence of Ralstonia solanacearum by controlling detoxification of phenolic acids and type III secretion system.Molecular plant pathology · 2019Article
- Metabolomic Profiling of the Host Response of Tomato (International journal of molecular sciences · 2019Article
- MarR Family Transcription Factors fromMicrobiology and molecular biology reviews : MMBR · 2019Review
- Biocontrol of Bacterial Wilt Disease Through Complex Interaction Between Tomato Plant, Antagonists, the Indigenous Rhizosphere Microbiota, andFrontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
Plants produce hydroxycinnamic acid (HCA) defense compounds to combat pathogens, such as the bacterium Ralstonia solanacearum. We showed that an HCA degradation pathway is genetically and functionally conserved across diverse R. solanacearum strains. Further, a feruloyl-CoA synthetase (Δfcs) mutant that cannot degrade HCA was less virulent on tomato plants. To understand the role of HCA degradation in bacterial wilt disease, we tested the following hypotheses: HCA degradation helps the pathogen i) grow, as a carbon source; ii) spread, by reducing HCA-derived physical barriers; and iii) survive plant antimicrobial compounds. Although HCA degradation enabled R. solanacearum growth on HCA in vitro, HCA degradation was dispensable for growth in xylem sap and root exudate, suggesting that HCA are not significant carbon sources in planta. Acetyl-bromide quantification of lignin demonstrated that R. solanacearum infections did not affect the gross quantity or distribution of stem lignin. However, the Δfcs mutant was significantly more susceptible to inhibition by two HCA, namely, caffeate and p-coumarate. Finally, plant colonization assays suggested that HCA degradation facilitates early stages of infection and root colonization. Together, these results indicated that ability to degrade HCA contributes to bacterial wilt virulence by facilitating root entry and by protecting the pathogen from HCA toxicity.
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