ArticleIranian journal of basic medical sciences2014
Antimicrobial susceptibility and analysis of macrolide resistance genes in Streptococcus pneumoniae isolated in Hamadan.
Article in Iranian journal of basic medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A metagenomic survey reveals widespread antibiotic resistance genes in honey bee (Applied and environmental microbiology · 2026Article
- Article
- Seasonal Azithromycin Use in Paediatric Protracted Bacterial Bronchitis Does Not Promote Antimicrobial Resistance but Does Modulate the Nasopharyngeal Microbiome.International journal of molecular sciences · 2023Observational
- Serotype Distribution and Multi Locus Sequence Type (MLST) of Erythromycin-ResistantReports of biochemistry & molecular biology · 2023Article
- Developing erythromycin resistance gene by heavy metals, Pb, Zn, and Co, in aquatic ecosystems.Scientific reports · 2022Article
- Virulence factors and antibiotic resistance properties of Streptococcus species isolated from hospital cockroaches.3 Biotech · 2021Article
- Is Penicillin-NonsusceptibleScientifica · 2021Article
- Antimicrobial profile of multidrug-resistantJournal of advanced veterinary and animal research · 2020Article
- Article
- High Frequency of Macrolide-ResistantTanaffos · 2019Article
- Resistance ofTanaffos · 2019Article
- Prevalence of nasopharyngeal carriage ofHuman vaccines & immunotherapeutics · 2019Article
- Antibiotics susceptibility pattern of Streptococcus pneumoniae isolated from sputum cultures of human immunodeficiency virus infected patients in Yaoundé, Cameroon.The Pan African medical journal · 2018Article
- Eradication of Helicobacter pylori in Children by Triple Therapy Regimens of Amoxicillin, Omeprazole, and Clarithromycin or Azithromycin.Iranian journal of pediatrics · 2015Article
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5 authors.
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Abstract
objectivesMacrolide resistant Streptococcus pneumoniae pose an emerging problem globally. The aim of this study was to investigate the prevalence of ermB and mefA genes (macrolide resistant genes) by polymerase chain reaction (PCR) method and to detect drug resistance patterns of S. pneumoniae isolated from clinical samples to macrolides and other antibiotic agents by E-test method. MATERIALS AND
methodsFifty five isolates of S. pneumoniae were obtained from clinical samples with microbial tests. The antibiotic susceptibility of isolates for erythromycin, azithromycin, clarithromycin, ceftazidime, ciprofloxacin and vancomycin were determined by E-test method. Genotypic antibiotic resistance pattern was determined by PCR with primer designed for ermB and mefA genes.
resultsThe number of S. pneumoniae isolates resistance to erythromycin, azithromycin, clarithromycin, ceftazidim, ciprofloxacin were 25.5%, 18.2%, 16.4%, 21.8% and 10.9%, respectively while no resistance to vancomycin was observed. The macrolide resistance genes of ermB and mefA were found in 10.9% and 18.2% of the isolates, respectively.
conclusionThe result of the current study suggests the necessity of evaluation the changes in MIC (minimum inhibitory concentration) values as well as genetic mutations to estimate the prevalence of the resistance antimicrobial agents in S. pneumoniae.
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25422753PMC4240794What OpenQuestion holds
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