Evidence map›Paper›PMID 25422662›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2014

Anethum graveolens and hyperlipidemia: A randomized clinical trial.

Mahmoud Mirhosseini, Azar Baradaran, Mahmoud Rafieian-Kopaei

Open access · greenAbstract read
In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  8. A review of plant-based compounds and medicinal plants effective on atherosclerosis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017
    Review
  9. Melatonin and human mitochondrial diseases.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017
    Review
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  11. The Role ofJournal of tropical medicine · 2016
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  14. Antifungal effects ofInternational journal of pharmaceutical investigation
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  15. In vitro andAvicenna journal of phytomedicine
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mahmoud MirhosseiniMedical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Azar BaradaranDepartment of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mahmoud Rafieian-KopaeiMedical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Shahrekord University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been established that hyperlipidemia increases the incidence and mortality associated with coronary heart disease. In this study, the effects of Dill (Anethum graveolens) were evaluated on lipid profile of hypercholesterolemic patients. MATERIALS AND

methodsIn this clinical study, 91 hyperlipidemic patients were randomly designated into two groups. One group received gemfibrozil (900 mg daily) and the other group received Dill tablet (six tablets daily) for 2 months. The blood lipids including total cholesterol, triglyceride and high density lipoprotein (HDL)-cholesterol from each group were assessed at the beginning and end of the trial.

resultsUse of gemfibrozil brought about increased HDL-cholesterol by 3.91% (P < 0.05) and reduced triglyceride and total cholesterol by 32.7% (P < 0.05) and 9.41% (P < 0.05), respectively. Applying Dill tablet for 2 months resulted in reduction of total cholesterol up to 18% (P < 0.05) and triglyceride by 7.38% (P < 0.05). However, circulating HDL-cholesterol was not affected by this treatment. In this study, gemfibrozil decreased triglyceride and increased HDL-cholesterol more than anethum (P < 0.05). Anethum decreased total cholesterol more than gemfibrozil (P < 0.05). Patients treated with anethum did not report any side effects.

conclusionThe results of this trial indicate that Dill might be beneficial for hypercholesterolemic and hypertriglycemic patients.

Indexed as

Anethum graveolensgemfibrozilhigh density lipoprotein-cholesteroltotal cholesteroltriglyceride

Identifiers

PMID25422662
PMCPMC4235097
OpenAlexW2096237273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.