ReviewSaudi journal of anaesthesia2014
Propofol alternatives in gastrointestinal endoscopy anesthesia.
Review in Saudi journal of anaesthesia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03196479 (Comparison Between Efficacy of Ketamine and Propofol Mixture With 1), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison Between Efficacy of Ketamine and Propofol Mixture With 1:6 Ratio and 1:4 Ratio for Endoscopic Retrograde Procedure Sedation
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Optimal remimazolam dosage for pediatric painless gastrointestinal endoscopy: a randomized controlled trial comparing efficacy and safety of three doses combined with sufentanil and propofol.BMC anesthesiology · 2026Trial
- Trial
- Remimazolam mitigates oxidative stress response in patients undergoing one-lung ventilation.Frontiers in surgery · 2025Article
- Remimazolam Compared to Propofol During Hysteroscopy: A Safety and Efficacy Analysis.Pain and therapy · 2023Article
- Advances in Analgosedation and Periprocedural Care for Gastrointestinal Endoscopy.Life (Basel, Switzerland) · 2023Review
- Article
- New sedatives and analgesic drugs for gastrointestinal endoscopic procedures.Clinical endoscopy · 2022Review
- A comprehensive review of remimazolam for sedation.Health psychology research · 2021Review
- Recent Developments in Drugs for GI Endoscopy Sedation.Digestive diseases and sciences · 2020Review
- Big Sleep: Beyond Propofol Sedation During GI Endoscopy.Digestive diseases and sciences · 2019Article
- Providing Deep Sedation for Advanced Endoscopic Procedures: The Esthetics of Endoscopic Anesthetics.Digestive diseases and sciences · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although propofol has been the backbone for sedation in gastrointestinal endoscopy, both anesthesiologists and endoscopists are faced with situations where an alternative is needed. Recent national shortages forced many physicians to explore these options. A midazolam and fentanyl combination is the mainstay in this area. However, there are other options. The aim of this review is to explore these options. The future would be, invariably, to move away from propofol. The reason is not in any way related to the drawbacks of propofol as a sedative. The mandate that requires an anesthesia provider to administer propofol has been a setback in many countries. New sedative drugs like Remimazolam might fill this void in the future. In the meantime, it is important to keep an open eye to the existing alternatives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.