ReviewClinical, cosmetic and investigational dentistry2014
The effect of xylitol on dental caries and oral flora.
Review in Clinical, cosmetic and investigational dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.
- Effect of xylitol on Porphyromonas gingivalis: A systematic review.Clinical and experimental dental research · 2023Pooled it
- Clinical effectiveness of theobromine, Remin Pro, and their combination in managing dentin hypersensitivity: a randomized clinical trial.BMC oral health · 2026Trial
- Effects of xylitol impregnated toothbrushes on periodontal status and microbial flora in orthodontic patients.The Angle orthodontist · 2020Trial
- Acquisition of a gene cluster inmSphere · 2026Article
- Remineralizing and Antimicrobial Effects of a Chitosan-Xylitol Hydrogel on Dental Enamel: An In Vitro Study.Gels (Basel, Switzerland) · 2026Article
- Xerostomia as an oral-systemic indicator: Etiology, diagnostic strategies and multimodal management approaches.Bioinformation · 2026Article
- The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications.Journal of oral microbiology · 2026Review
- Xylitol Modification of Electrospun Polymer Scaffolds: Impact on Physicochemical and Antibacterial Properties.Polymers · 2025Article
- Review
- Inhibition ofFrontiers in microbiology · 2025Article
- Every bite counts to achieve oral health: a scoping review on diet and oral health preventive practices.International journal for equity in health · 2024Article
- Comparative Evaluation of Plaque Removal Potential of Manual Electrical and Chewable Toothbrushes in Children: A Clinical Trial.International journal of clinical pediatric dentistry · 2024Article
- Is xylitol effective in the prevention of dental caries? A systematic review.Journal of clinical and experimental dentistry · 2024Review
- Phytochemical profile and antimicrobial activity ofHeliyon · 2024Article
- Oral Microbiome: A Review of Its Impact on Oral and Systemic Health.Microorganisms · 2024Review
- Alteration of oral microbial biofilms by sweeteners.Biofilm · 2024Review
- Do chewing gums and sweets containing xylitol prevent caries in children?Evidence-based dentistry · 2024Article
- Prevention of Dental Caries: A Review on the Improvements of Toothpaste Formulations from 1900 to 2023.Dentistry journal · 2024Review
- Comprehensive in vitro and in ovo assessment of cytotoxicity: Unraveling the impact of sodium fluoride, xylitol, and their synergistic associations in dental products.Biomolecules & biomedicine · 2024Article
- Evaluation of caries risk assessment practices among dental practitioners in Guangzhou, China: a cross-sectional study.Frontiers in oral health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental caries, the most chronic disease affecting mankind, has been in the limelight with regard to its prevention and treatment. Professional clinical management of caries has been very successful in cases of different severities of disease manifestations. However, tertiary management of this disease has been gaining attention, with numerous methods and agents emerging on a daily basis. Higher intake of nutritive sweeteners can result in higher energy intake and lower diet quality and thereby predispose an individual to conditions like obesity, cardiovascular disorders, and type 2 diabetes mellitus. Non-nutritive sweeteners have gained popularity as they are sweeter and are required in substantially lesser quantities. Xylitol, a five-carbon sugar polyol, has been found to be promising in reducing dental caries disease and also reversing the process of early caries. This paper throws light on the role and effects of various forms of xylitol on dental caries and oral hygiene status of an individual.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.