Evidence map›Paper›PMID 25422563›Full record

ArticleJournal of pharmacology & pharmacotherapeutics2014

Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation.

Ravi Venkatachelam Chitrapu, Pentakota Ramana Rao, Gangireddy Venkateswara Reddy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of pharmacology & pharmacotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ravi Venkatachelam ChitrapuDepartment of Cardiology, Andhra Medical College, King George Hospital, Visakhapatnam, Andhra Pradesh, India.
Pentakota Ramana RaoDepartment of Cardiology, Andhra Medical College, King George Hospital, Visakhapatnam, Andhra Pradesh, India.
Gangireddy Venkateswara ReddyDepartment of Cardiology, Andhra Medical College, King George Hospital, Visakhapatnam, Andhra Pradesh, India.
King George Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND

methodsIn an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d.

resultsA successful result was seen in 25 patients (71.4%) with 4 converting to sinus rhythm, rate control to less than 90 bpm in 16 and a 20% rate reduction in 5 patients. Two patients developed hypotension needing withdrawal of the drug.

conclusionEscalating doses of oral carvedilol can be effectively and safely used in the acute treatment of AF with fast ventricular rate.

Indexed as

Acute treatmentatrial fibrillationcarvediloloral tabletrate control

Identifiers

PMID25422563
PMCPMC4231552
OpenAlexW2082907391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.