ArticlePharmacognosy magazine2014
Effects of ginsenosides-Rb1 on exercise-induced oxidative stress in forced swimming mice.
Article in Pharmacognosy magazine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Trial
- Beyond the pill: incrimination of nuclear factor-kappa B and their targeted phytomedicine for pulmonary fibrosis.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Comprehensive understanding and underlying molecular mechanisms of the adaptogenic effects ofJournal of ginseng research · 2025Review
- Ginsenosides, salidroside, and syringin complex exhibits anti-fatigue in exhaustive exercise rats.International journal of medical sciences · 2025Article
- Effect of Ginseng Supplementation on Exercise Endurance as a Support for Cardiovascular Disease Management: A Systematic Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2024Review
- Investigation of Ginseng-Ophiopogon Injection on Enhancing Physical Function by Pharmacogenomics and Metabolomics Evaluation.Combinatorial chemistry & high throughput screening · 2024Article
- Ginsenoside Rb1 improves energy metabolism after spinal cord injury.Neural regeneration research · 2023Article
- Ginsenoside Rf Enhances Exercise Endurance by Stimulating Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes and ICR Mice.Foods (Basel, Switzerland) · 2022Article
- Quantitative Comparison and Chemical Profile of Different Botanical Parts ofFrontiers in nutrition · 2022Article
- Urinary Proteomics of Simulated Firefighting Tasks and Its Relation to Fitness Parameters.International journal of environmental research and public health · 2021Article
- Application of traditional Chinese therapy in sports medicine.Sports medicine and health science · 2021Review
- Dammarane-type triterpene ginsenoside-Rg18 inhibits human non-small cell lung cancer A549 cell proliferation via GOncology letters · 2018Article
- The Effects of a Korean Ginseng, GINST15, on Perceptual Effort, Psychomotor Performance, and Physical Performance in Men and Women.Journal of sports science & medicine · 2018Article
- A New Model of Diarrhea with Spleen-Kidney Yang Deficiency Syndrome.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Muscle fatigue: general understanding and treatment.Experimental & molecular medicine · 2017Review
- Effects of Laminaria japonica polysaccharides on exercise endurance and oxidative stress in forced swimming mouse model.Journal of biological research (Thessalonike, Greece) · 2016Article
- Effects of Resveratrol Supplementation on Oxidative Damage and Lipid Peroxidation Induced by Strenuous Exercise in Rats.Biomolecules & therapeutics · 2015Article
- Anti-Fatigue Effect of Green Tea Polyphenols (-)-Epigallocatechin-3-Gallate (EGCG).Pharmacognosy magazineArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe fleshy root of Panax ginseng C.A. Meyer (ginseng) is one of the most well-known and valued herbs in traditional Chinese medicine. Ginsenosides are considered mainly responsible for the pharmacological activities of ginseng. The purpose of this study was to investigate the effects of ginsenoside-Rb1 (G-Rb1) on swimming exercise-induced oxidative stress in male mice. MATERIALS AND
methodsA total of 48 animals were randomly divided into four groups, with twelve mice in each group. The first, second and third groups were designed as G-Rb1 treatment groups, got 25, 50 and 100 mg/kg bodyweight of G-Rb1, respectively. The fourth group was designed as the control group, got physiologic saline. The mice were intragastrically administered once daily for 4 weeks. The weight-loaded forced swimming test was conducted on the final day of experimentation. Then the exhaustive swimming time, blood lactate, serum creatine kinase (CK), malondialdehyde (MDA) and antioxidant enzymes in liver of mice were measured.
resultsThe results showed that G-Rb1 could prolong the exhaustive swimming time and improve exercise endurance capacity of mice, as well as accelerate the clearance of blood lactate and decrease serum CK activities. Meanwhile, G-Rb1 could decrease MDA contents and increase superoxide dismutase, catalase, glutathione peroxidase activities in liver of mice.
conclusionsThe study suggested that G-Rb1 possessed protective effects on swimming exercise-induced oxidative stress in mice.
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