Evidence map›Paper›PMID 25422150›Full record

ReviewArchives of women's mental health2015

Preventing postpartum depression: review and recommendations.

Elizabeth Werner, Maia Miller, Lauren M Osborne, Sierra Kuzava, Catherine Monk

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Archives of women's mental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06818734 (Implementation of a Clinical Decision Support Tool for Postpartum Depression), which is not on this map. Cited by 77 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 8 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06818734 narecruitingnot on this mapstarted 2026, after this paper: background citation

Implementation of a Clinical Decision Support Tool for Postpartum Depression

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2026 to 2026Enrolled160ConditionsPostpartum DepressionArmsClinical Decision Support Tool
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 8 syntheses or guidelines pooled it, 211 citations in OpenAlex.

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  16. Selective dietary supplementation in early postpartum is associated with high resilience against depressed mood.Proceedings of the National Academy of Sciences of the United States of America · 2017
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elizabeth WernerBehavioral Medicine Division, Department of Psychiatry, Columbia University Medical Center, 630 W 168th St, PH1540H, New York, NY, 10032, USA, ew150@columbia.edu.
Maia Miller
Lauren M Osborne
Sierra Kuzava
Catherine Monk
Columbia University Irving Medical Center · USJohns Hopkins Medicine · US

Funding

Research Training in Mood and Anxiety Disorders: From Animal Models to PatientsT32MH015144 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Eduardo David Leonardo · 1985 to 2026
$11.1M
Behavioral Change in the Mother/Infant Dyad: Preventing Postpartum DepressionR21MH092665 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MONK, CATHERINE E · 2011 to 2012
$441k
NIMH NIH HHS R21 MH092665NIMH NIH HHS T32 MH015144
6 · The paper itself

Abstract

Nearly 20 % of mothers will experience an episode of major or minor depression within the first 3 months postpartum, making it the most common complication of childbearing. Postpartum depression (PPD) is significantly undertreated, and because prospective mothers are especially motivated for self-care, a focus on the prevention of PPD holds promise of clinical efficacy. This study is a qualitative review of existing approaches to prevent PPD. A PubMed search identified studies of methods of PPD prevention. The search was limited to peer-reviewed, published, English-language, randomized controlled trials (RCTs) of biological, psychological, and psychosocial interventions. Eighty articles were initially identified, and 45 were found to meet inclusion criteria. Eight RCTs of biological interventions were identified and 37 RCTs of psychological or psychosocial interventions. Results were mixed, with 20 studies showing clear positive effects of an intervention and 25 showing no effect. Studies differed widely in screening, population, measurement, and intervention. Among biological studies, anti-depressants and nutrients provided the most evidence of successful intervention. Among psychological and psychosocial studies, 13/17 successful trials targeted an at-risk population, and 4/7 trials using interpersonal therapy demonstrated success of the intervention versus control, with a further two small studies showing trends toward statistical significance. Existing approaches to the prevention of PPD vary widely, and given the current literature, it is not possible to identify one approach that is superior to others. Interpersonal therapy trials and trials that targeted an at-risk population appear to hold the most promise for further study.

Indexed as

Depression, PostpartumFemaleHumansMothersPsychotherapyRandomized Controlled Trials as TopicSocial Support

Identifiers

PMID25422150
PMCPMC4308451
OpenAlexW2042783002

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.