Evidence map›Paper›PMID 25422034›Full record

ArticleJournal of experimental & clinical cancer research : CR2014

Direct to implant breast reconstruction by using SERI, preliminary report.

Roy De Vita, Ernesto Maria Buccheri, Marcello Pozzi, Giovanni Zoccali

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of experimental & clinical cancer research : CR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03673449 (A Pilot Study to Evaluate the Reconstruction of Digital Nerve Defects in Humans Using an Implanted Silk Nerve Guide), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03673449 naunknown statusnot on this mapstarted 2019, after this paper: background citation

A Pilot Study to Evaluate the Reconstruction of Digital Nerve Defects in Humans Using an Implanted Silk Nerve Guide

TypeinterventionalSponsorSilk Biomaterials srlRan2019 to 2021Enrolled4ConditionsPeripheral Nerve Injury Digital Nerve HandArmsSilkBridge
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Skin-sparing mastectomy.Gland surgery · 2015
    Review
  6. Skin-reducing mastectomy and immediate breast reconstruction in patients with macromastia.Journal of experimental & clinical cancer research : CR · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Roy De VitaPlastic Surgery Department, Regina Elena Cancer Institute of Rome, Rome, Italy. roydevita@roydevita.it.
Ernesto Maria BuccheriPlastic Surgery Department, Regina Elena Cancer Institute of Rome, Rome, Italy. buccheriernesto@libero.it.
Marcello PozziPlastic Surgery Department, Regina Elena Cancer Institute of Rome, Rome, Italy. mpozzi@ifo.it.
Giovanni ZoccaliPlastic Surgery Department, Regina Elena Cancer Institute of Rome, Rome, Italy. zoccali.giovanni@virgilio.it.
National Cancer Institute · MYIstituti Fisioterapici Ospitalieri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been a "rising tide" in mastectomy utilization that can be attributed to more skin-sparing mastectomies (SSMs) performed concurrently with immediate breast reconstruction. We report our experience of the first use of SERI Surgical Scaffold (SERI; Allergan, Inc.) in 21 cases of direct to implant (DTI) breast reconstruction after SSM.

methodsOur retrospective experience, from April 2013 to May 2014, is based on 21 cases of direct to implant (DTI) breast reconstruction after SSM (9 monolateral 6 bilateral). All the patients were oncological with a preoperative cancer stage was into 0-2 stage. In order to assess the level of satisfaction with the aesthetical result, on 4-13 months post-operative patients were asked to complete a questionnaire that evaluated various parameters by means of a Visual Analogue Scale (V.A.S.).

resultsOver a 13-months period, a total of 15 patients underwent 21 immediate breast reconstructive procedures with Allergan Natrelle 410 style implants plus SERI after SSMs. Definitive histological examination give evidence of 5 patients intraductal carcinoma, 6 patients multifocal carcinoma and 4 patients carcinoma in situ. 6 bilateral cases of direct to implant (DTI) breast reconstruction after SSM had a monolateral oncological treatment and on the other side a prophylactic treatment. At the end of the short follow up (minimum 6 months) all the patient were cancer free with an excellent outcome. Complication rate presents just one implant exposure followed by a revised surgery. At V.A.S. the mean patient satisfaction was 5,77 (good), 4,09 (fair) for sensitivity of the nipple areola complex, 6,33 (good) assessment of implant position, 6,28 (good) self esteem, 5,2 (good) attraction ability, 4,99 (fair) intimate life, 6,81 (good) overall feelings about breast reconstruction, 6,71 (good) simmetry.

conclusionsThe really encouraging results of our early experience will help surgeons introducing SERI into their practice to select appropriate patients for direct-to-implant single-stage immediate breast reconstruction. A larger study cohort and longer follow-up times are required to identify additional predictors and indications.

Indexed as

Breast ImplantsTissue ScaffoldsAdultBreast ImplantationBreast NeoplasmsFemaleHumansMastectomyMiddle AgedNeoplasm StagingPatient SatisfactionPostoperative ComplicationsReoperationRetrospective StudiesSurveys and QuestionnairesTime Factors

Identifiers

PMID25422034
PMCPMC4268891
OpenAlexW2160615213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.