Evidence map›Paper›PMID 25421896›Full record

ArticleViruses2014

Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014.

Jens H Kuhn, Kristian G Andersen, Sylvain Baize, Yīmíng Bào, Sina Bavari, Nicolas Berthet, Olga Blinkova, J Rodney Brister, Anna N Clawson, Joseph Fair and 34 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Impact of RNA Virus Evolution on Quasispecies Formation and Virulence.International journal of molecular sciences · 2019
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Jens H KuhnIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. kuhnjens@mail.nih.gov.
Kristian G AndersenFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. kandersen@oeb.harvard.edu.
Sylvain BaizeUnité de Biologie des Infections Virales Emergentes, Institut Pasteur, Lyon, France. sylvain.baize@inserm.fr.
Yīmíng BàoInformation Engineering Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. bao@ncbi.nlm.nih.gov.
Sina BavariUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. sina.bavari.civ@mail.mil.
Nicolas BerthetCentre International de Recherches Médicales de Franceville, B. P. 769, Franceville, Gabon. nicolas.berthet@pasteur.fr.
Olga BlinkovaInformation Engineering Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. olga.blinkova@nih.gov.
J Rodney BristerInformation Engineering Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. jamesbr@ncbi.nlm.nih.gov.
Anna N ClawsonIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. anna@logosconsulting.us.
Joseph FairFondation Mérieux, Washington, DC 20036, USA. joseph.fair@fondation-merieux.org.
Martin GabrielBernhard Nocht Institute for Tropical Medicine, World Health Organization (WHO) Collaborating Center for Arbovirus and Hemorrhagic Fever Reference and Research, and the German Center for Infection Research (DZIF), Partner Site Hamburg, 20259 Hamburg, Germany. gabriel@bni-hamburg.de.
Robert F GarryTulane University School of Medicine, New Orleans, LA 70112, USA. rfgarry@tulane.edu.
Stephen K GireFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. sgire@oeb.harvard.edu.
Augustine GobaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. augstgoba@yahoo.com.
Jean-Paul GonzalezIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. jpgonzalez@metabiota.com.
Stephan GüntherBernhard Nocht Institute for Tropical Medicine, World Health Organization (WHO) Collaborating Center for Arbovirus and Hemorrhagic Fever Reference and Research, and the German Center for Infection Research (DZIF), Partner Site Hamburg, 20259 Hamburg, Germany. guenther@bni.uni-hamburg.de.
Christian T HappiIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. happic@run.edu.ng.
Peter B JahrlingIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. jahrlingp@niaid.nih.gov.
Jimmy KapetshiIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. jimmy_kap@hotmail.com.
Gary KobingerIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. gary.kobinger@phac-aspc.gc.ca.
Jeffrey R KugelmanUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. jeffrey.r.kugelman.mil@mail.mil.
Eric M LeroyCentre International de Recherches Médicales de Franceville, B. P. 769, Franceville, Gabon. eric.leroy@ird.fr.
Gael Darren MagangaCentre International de Recherches Médicales de Franceville, B. P. 769, Franceville, Gabon. gael_maganga@yahoo.fr.
Placide K MbalaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. mbalaplacide@gmail.com.
Lina M MosesTulane University School of Medicine, New Orleans, LA 70112, USA. lmoses2@tulane.edu.
Jean-Jacques Muyembe-TamfumIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. muyembejj@gmail.com.
Magassouba N'FalyIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. cmagassouba01@gmail.com.
Stuart T NicholIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. stn1@cdc.gov.
Sunday A OmilabuIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. omilabusa@yahoo.com.
Gustavo PalaciosUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. gustavo.f.palacios.ctr@us.army.mil.
Daniel J ParkIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. dpark@broadinstitute.org.
Janusz T PaweskaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. januszp@nicd.ac.za.
Sheli R RadoshitzkyUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. sheli.r.radoshitzky.ctr@mail.mil.
Cynthia A RossiUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. cynthia.a.rossi.civ@mail.mil.
Pardis C SabetiFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. pardis@broadinstitute.org.
John S SchieffelinTulane University School of Medicine, New Orleans, LA 70112, USA. jschieff@tulane.edu.
Randal J SchoeppUnited States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA. randal.j.schoepp.civ@mail.mil.
Rachel SealfonFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. sealfon@gmail.com.
Robert SwanepoelFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. bobswanepoel@gmail.com.
Jonathan S TownerIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. jit8@cdc.gov.
Jiro WadaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. wadaj@niaid.nih.gov.
Nadia WauquierIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. nadia.wauquier@gmail.com.
Nathan L YozwiakFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. nyozwiak@broadinstitute.org.
Pierre FormentyFAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. formentyp@who.int.

Funding

Integrated Research Facility at Fort DetrickZIDAI009006 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI COE, LINDA · 2009 to 2018
$341.7M
Antibody immunotherapeutics for biodefense against Lassa virusR01AI104621 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI GARRY, ROBERT F · 2013 to 2017
$5.8M
Project 2. Expansion of Clinical Research Capacity at Kenema Government HospitalU19AI115589 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI SCHIEFFELIN, JOHN SCRIBNER · 2015 to 2019
$3.6M
Intramural NIH HHSNIAID NIH HHS HHSN272200700016INIAID NIH HHS R01 AI104621NIAID NIH HHS U19 AI115589
6 · The paper itself

Abstract

In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological and evolutionary analyses confirmed that all cases of both outbreaks are connected to a single introduction each of EBOV into human populations and that both outbreaks are not directly connected. Coding-complete genomic sequence analyses of isolates revealed that the two outbreaks were caused by two novel EBOV variants, and initial clinical observations suggest that neither of them should be considered strains. Here we present consensus decisions on naming for both variants (West Africa: "Makona", Middle Africa: "Lomela") and provide database-compatible full, shortened, and abbreviated names that are in line with recently established filovirus sub-species nomenclatures.

Indexed as

Terminology as TopicDemocratic Republic of the CongoDisease OutbreaksEbolavirusGuineaHemorrhagic Fever, EbolaHumansPhylogenyRNA, ViralSequence Analysis, DNARNA, Viral

Identifiers

PMID25421896
PMCPMC4246247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.