ArticleMolecules (Basel, Switzerland)2014
Isolation and bioactivities of the flavonoids morin and morin-3-O-β-D-glucopyranoside from Acridocarpus orientalis-A wild Arabian medicinal plant.
Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Chemical Composition and Health-Promoting Effects of theNutrients · 2021Pooled it
- Biological activity, UHPLC-MS phytochemical profiling, and computational studies of the leaf extract of Acridocarpus socotranus.Scientific reports · 2025Article
- Research Progress of Bioactive Components inMolecules (Basel, Switzerland) · 2024Review
- Revision of NMR assignment for Morin-3-O-glucoside and microbial production of Morin-2'-O-glucoside.Journal of natural medicines · 2024Article
- Polymeric Systems for the Controlled Release of Flavonoids.Pharmaceutics · 2023Review
- Investigation of insecticidal activity of twoJournal of plant diseases and protection : scientific journal of the German Phytomedical Society (DPG) · 2023Article
- Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review.Frontiers in pharmacology · 2022Review
- Anti-5'-Nucleotidases (5'-ND) and Acetylcholinesterase (AChE) Activities of Medicinal Plants to CombatBioMed research international · 2021Article
- Secondary metabolites from acridocarpus orientalis inhibits 4T1 cells and promotes mesenchymal stem cells (MSCs) proliferation.Molecular biology reports · 2020Article
- Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.BMC complementary medicine and therapies · 2020Article
- Differential Cytotoxic Potential ofMolecules (Basel, Switzerland) · 2019Article
- Dietary Intervention by Phytochemicals and Their Role in Modulating Coding and Non-Coding Genes in Cancer.International journal of molecular sciences · 2017Review
- The Practice of Ethnomedicine in the Northern and Southern Provinces of Oman.Oman medical journal · 2016Review
- TLR4-MyD88-TRAF6-TAK1 Complex-Mediated NF-κB Activation Contribute to the Anti-Inflammatory Effect of V8 in LPS-Induced Human Cervical Cancer SiHa Cells.Inflammation · 2016Article
- Quantitative Phytochemical Constituents and Antioxidant Activities of the Mistletoe,Pharmacognosy researchArticle
- The role of flavonoid antioxidant, morin in improving procarbazine-induced oxidative stress on testicular function in rat.Porto biomedical journalArticle
- The effects of morin on bone regeneration to accelerate healing in bone defects in mice.International journal of immunopathology and pharmacologyArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acridocarpus orientalis is an important medicinal plant for some of the locals of Arabian region. Very little is known about its phytochemical constituents. In the present study, we aimed to isolate bioactive chemicals from the crude methanolic extract of the aerial parts of A. orientalis. The extraction and isolation resulted in the purification of two flavonoids: morin (1) and morin-3-O-β-D-glucopyranoside (2). The structure elucidation was carried out by extensive analysis of spectroscopic data and comparison with the reported data for the known constituents. The pure isolates were subjected to various biological assays for their bioactivities. The compounds 1 and 2 were significantly active against the growth of various pathogenic fungi and phytotoxic against lettuce seed at higher concentrations. Furthermore, the free radical scavenging activities, anti-lipid peroxidation, and cytotoxic effects against HepG2, HT29, and HCT116 cancer cell lines were also assayed and the results are presented in this paper.
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