Evidence map›Paper›PMID 25421363›Full record

Trial reportBMC family practice2014

Cost-effectiveness of chronic fatigue self-management versus usual care: a pilot randomized controlled trial.

Hongdao Meng, Fred Friedberg, Melissa Castora-Binkley

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC family practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00997451 (Fatigue Self- Management in Primary Care), which is not on this map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00997451 nacompletednot on this map

Fatigue Self- Management in Primary Care: Efficacy, Credibility, and Economics

TypeinterventionalSponsorStony Brook UniversityRan2009 to 2011Enrolled107ConditionsMedically Unexplained Chronic Fatigue, Chronic Fatigue SyndromeArmsCognitive-behavioral self-management, Symptom monitoring
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. CBT to reduce healthcare use for medically unexplained symptoms: systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hongdao Meng
Fred Friedberg
Melissa Castora-Binkley
University of South Florida · USStony Brook University · US

Funding

Fatigue Self-Management in Primary Care: Efficacy, Credibility, and EconomicsR01NR010229 · NINR · STATE UNIVERSITY NEW YORK STONY BROOK · PI FRIEDBERG, FRED · 2008 to 2011
$916k
NINR NIH HHS R01 NR010229NINR NIH HHS R01NR010229
6 · The paper itself

Abstract

backgroundFatigue is a common yet difficult to treat condition in primary care. The objective of this study is to evaluate the cost-effectiveness of a brief cognitive behavioral therapy (CBT) based fatigue self-management (FSM) intervention as compared to usual care among patients with chronic fatigue in primary care.

methodsAn economic evaluation alongside of a parallel randomized controlled study design was used. Computer-generated variable-sized block randomization plan was used to assign patients into treatment groups and data collection staff were blinded to group assignments. Patients aged between 18 and 65 years with at least six months of persistent fatigue and no medical or psychiatric exclusions were enrolled from a large primary care practice in Stony Brook, New York. The FSM group (n = 37) received two sessions of a nurse-delivered, fatigue self-management protocol and a self-help book and the usual care group (n = 36) received regular medical care. The effectiveness measure was the Fatigue Severity Scale and the cost measure was total health care expenditures derived from monthly health services use diaries during follow-up. A societal perspective was adopted and bootstrapped incremental cost-effectiveness ratios (ICERs) and net monetary benefit (NMB) were calculated as measures of cost-effectiveness.

resultsThe ICER for FSM was -$$2358, indicating that FSM dominates UC and it may generate societal cost savings as compared to usual care. Complete case analysis yielded smaller ICER (-$1199) with greater uncertainties. Net monetary benefit analysis showed that FSM has a probability of 0.833 (95% CI: 0.819, 0.847) to achieve positive NMB and the favorable results were not sensitive to assumptions about informal care or treatment costs.

conclusionThis economic evaluation found initial evidence that a two-session brief CBT-based FSM may be cost-effective as compared to usual care over 12 months. The FSM intervention is potentially a promising intervention for chronic fatigue patients in primary care. Additional research is needed to examine the reproducibility and generalizability of these findings.

trial registrationClinicalTrials.gov (NCT00997451, March 28, 2009).

Indexed as

AdolescentAdultAgedCognitive Behavioral TherapyCost-Benefit AnalysisFatigue Syndrome, ChronicFemaleHealth Care CostsHealth ExpendituresHealth ServicesHumansMaleMiddle AgedPilot ProjectsSelf CareYoung Adult

Identifiers

PMID25421363
PMCPMC4260238
OpenAlexW2061649809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.